SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
X	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* BB BIOVENTURES L P (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol OSCIENT PHARMACEUTICALS CORP [ OSCI ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner
	3. Date of Earliest Transaction (Month/Day/Year) 08/15/2005
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/15/2005		S		50,000(1)	D	$2.607	7,482,050	I	See footnote(2)
Common Stock	08/16/2005		S		150,000(3)	D	$2.6424	7,332,050	I	See footnote(4)
Common Stock	08/17/2005		S		160,000(5)	D	$2.6615	7,172,050	I	See footnote(6)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* BB BIOVENTURES L P (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* MPM BIO VENTURES PARALLEL FUND L P (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* MPM ASSET MANAGEMENT INVESTORS 1998 LLC/MA (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* BAB BIO VENTURES LLP (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* BAB BIO VENTURES NV (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* MPM BIO VENTURES I LP (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* MPM BIO VENTURES I LLC (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* GADICKE ANSBERT (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* STEINMETZ MICHAEL (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

1. Name and Address of Reporting Person* EVNIN LUKE (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVE., 31ST FLOOR (Street) BOSTON MA 02199 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer X Director 10% Owner Officer (give title below) X Other (specify below) Former 10% owner

Explanation of Responses:

1. The shares were sold as follows: 43,800 by BB BioVentures L.P. ("BB BV"), 5,626 by MPM BioVentures Parallel Fund, L.P. ("BV PF") and 575 by MPM Asset Management Investors 1998 LLC ("AM 1998"). MPM BioVentures I, L.P. ("BV I") and MPM BioVentures I LLC ("BV I LLC") are the direct and indirect general partners of BV PF. BAB BioVentures L.P. ("BAB BV") and BAB BioVentures, N.V. ("BAB NV") are the direct and indirect general partners of BB BV. Luke Evnin, Ansbert Gadicke and Michael Steinmetz are the managers of BAB NV, AM 1998 and BV I LLC.

2. The shares are held as follows: 6,052,862 by BB BV, 777,393 by BV PF and 79,459 by AM 1998. Each member of the group disclaims beneficial ownership of the securities except to the extent of its pecuniary interest therein.

3. The shares were sold as follows: 131,399 by BB BV, 16,876 by BV PF and 1,725 by AM 1998.

4. The shares are held as follows: 6,421,758 by BB BV, 825,976 by BV PF and 84,316 by AM 1998. Each member of the group disclaims beneficial ownership of the securities except to the extent of its pecuniary interest therein.

5. The shares were sold as follows: 140,136 by BB BV, 18,024 by BV PF and 1,840 by AM 1998.

6. The shares are held as follows: 6,281,622 by BB BV, 807,952 by BV PF and 82,476 by AM 1998. Each member of the group disclaims beneficial ownership of the securities except to the extent of its pecuniary interest therein.

	By Luke Evnin, manager of BAB BioVentures, N.V., the general partner of BB BioVentures L.P. /s/ Luke Evnin	08/17/2005
	By Luke Evnin, manager of MPM BioVentures I L.P. and MPM BioVentures I LLC, the general partners of BB BioVentures Parallel Fund, L.P. /s/ Luke Evnin	08/17/2005
	By Luke Evnin, manager of MPM Asset Management Investors 1998 LLC. /s/ Luke Evnin	08/17/2005
	By Luke Evnin, manager of BAB BioVentures, N.V., the general partner of BAB BioVentures L.P. /s/ Luke Evnin	08/17/2005
	By Luke Evnin, manager of BAB BioVentures, N.V. /s/ Luke Evnin	08/17/2005
	By Luke Evnin, manager of MPM BioVentures I LLC, the general partner of MPM BioVentures I L.P. /s/ Luke Evnin	08/17/2005
	By Luke Evnin, manager of MPM BioVentures I LLC. /s/ Luke Evnin	08/17/2005
	/s/ Michael Steinmetz	08/17/2005
	/s/ Ansbert Gadicke	08/17/2005
	/s/ Luke Evnin	08/17/2005
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.