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0001172661-19-001382.txt : 20190515 0001172661-19-001382.hdr.sgml : 20190515 20190515162448 ACCESSION NUMBER: 0001172661-19-001382 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20190331 FILED AS OF DATE: 20190515 DATE AS OF CHANGE: 20190515 EFFECTIVENESS DATE: 20190515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: ORBIMED ADVISORS LLC CENTRAL INDEX KEY: 0001055951 IRS NUMBER: 133976876 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-06774 FILM NUMBER: 19828621 BUSINESS ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: (212) 739-6400 MAIL ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001055951 XXXXXXXX 03-31-2019 03-31-2019 false ORBIMED ADVISORS LLC

601 Lexington Avenue 54th Floor New York NY 10022

13F HOLDINGS REPORT 028-06774 N Sven H. Borho Member 212-739-6400 /s/ Sven H. Borho New York NY 05-15-2019 1 124 6459711 1 0001157524 028-10410 ORBIMED CAPITAL LLC INFORMATION TABLE 2 infotable.xml ABBOTT LABS COM 002824100 49195 615400 SH DFND 1 250000 0 365400 ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 5808 1350655 SH SOLE 1350655 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 6514 1243200 SH SOLE 0 0 1243200 AEGERION PHARMACEUTICALS INC NOTE 2.000% 8/1 00767EAB8 1381 2000000 PRN DFND 1 419600 0 1580400 AEGLEA BIOTHERAPEUTICS INC COM 00773J103 17432 2165524 SH SOLE 2165524 0 0 AERIE PHARMACEUTICALS INC COM 00771V108 2755 58000 SH SOLE 0 0 58000 AERPIO PHARMACEUTICALS INC COM 00810B105 4680 5193946 SH SOLE 5193946 0 0 AGILENT TECHNOLOGIES INC COM 00846U101 64200 798700 SH DFND 1 210200 0 588500 ALECTOR INC COM 014442107 246773 13182329 SH DFND 1 12890829 0 291500 ALEXION PHARMACEUTICALS INC COM 015351109 264574 1957200 SH DFND 1 398400 0 1558800 ALPINE IMMUNE SCIENCES INC COM 02083G100 25183 3670955 SH SOLE 3670955 0 0 AMARIN CORP PLC SPONS ADR NEW 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