0001172661-19-000868.txt : 20190214 0001172661-19-000868.hdr.sgml : 20190214 20190214163505 ACCESSION NUMBER: 0001172661-19-000868 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20181231 FILED AS OF DATE: 20190214 DATE AS OF CHANGE: 20190214 EFFECTIVENESS DATE: 20190214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: ORBIMED ADVISORS LLC CENTRAL INDEX KEY: 0001055951 IRS NUMBER: 133976876 STATE OF INCORPORATION: DE FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-06774 FILM NUMBER: 19607219 BUSINESS ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: (212) 739-6400 MAIL ADDRESS: STREET 1: 601 LEXINGTON AVENUE STREET 2: 54TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10022 13F-HR 1 primary_doc.xml 13F-HR LIVE false true false 0001055951 XXXXXXXX 12-31-2018 12-31-2018 false ORBIMED ADVISORS LLC

601 Lexington Avenue 54th Floor New York NY 10022

13F HOLDINGS REPORT 028-06774 N Sven H. Borho 212-739-6400 /s/ Sven H. Borho New York NY 02-14-2019 1 131 5407812 1 0001157524 028-10410 ORBIMED CAPITAL LLC INFORMATION TABLE 2 infotable.xml 111 INC ADS 68247Q102 3070 500000 SH SOLE 0 0 500000 ABBOTT LABS COM 002824100 32433 448400 SH DFND 1 250000 0 198400 AC IMMUNE SA SHS H00263105 13608 1440000 SH SOLE 0 0 1440000 ADAMAS PHARMACEUTICALS INC COM 00548A106 854 100000 SH Call DFND 1 19000 0 81000 ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 7766 1350655 SH SOLE 1350655 0 0 AEGERION PHARMACEUTICALS INC NOTE 2.000% 8/1 00767EAB8 1676 2000000 PRN DFND 1 419600 0 1580400 AEGLEA BIOTHERAPEUTICS INC COM 00773J103 16220 2165524 SH SOLE 2165524 0 0 AERIE PHARMACEUTICALS INC COM 00771V108 31483 872100 SH DFND 1 200300 0 671800 AERPIO PHARMACEUTICALS INC COM 00810B105 8830 5193946 SH SOLE 5193946 0 0 AFFIMED N V COM N01045108 1016 326650 SH SOLE 326650 0 0 AGILENT TECHNOLOGIES INC COM 00846U101 50797 753000 SH DFND 1 164500 0 588500 ALEXION PHARMACEUTICALS INC COM 015351109 199335 2047400 SH DFND 1 426600 0 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