UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                   Under the Securities Exchange Act of 1934
                               (Amendment No.2 )*


                               Transgenomic, Inc.
                                (Name of Issuer)

                                  Common Stock
                         (Title of Class of Securities)

                                   89365K206
                                 (CUSIP Number)

                               December 31, 2010
            (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:
       [X]     Rule 13d-1(b)
       [ ]     Rule 13d-1(c)
       [ ]     Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class
of securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not
be deemed to be 'filed' for the purpose of Section 18 of the Securities
Exchange Act of 1934 ('Act') or otherwise subject to the liabilities of
that section of the Act but shall be subject to all other provisions of
the Act (however, see the Notes).

                                     Page 1

CUSIP No. 89365K206
- --------------------------------------------------------------------------------
1. Names of Reporting Persons.

Barclays PLC

- --------------------------------------------------------------------------------
2. Check the Appropriate Box if a Member of a Group (See Instructions)

(a) [ ]
(b) [ ]

- --------------------------------------------------------------------------------
3. SEC Use Only

- --------------------------------------------------------------------------------
4. Citizenship or Place of Organization

England

                        5. Sole Voting Power
Number of                  -0-
Shares              ------------------------------
Beneficially            6. Shared Voting Power
Owned by Each              -0-
Reporting           ------------------------------
Person With:            7. Sole Dispositive Power
                           -0-
                    ------------------------------
                        8. Shared Dispositive Power
                           -0-

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9. Aggregate Amount Beneficially Owned by Each Reporting Person

0

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10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares
               (See Instructions)  [ ]

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11. Percent of Class Represented by Amount in Row (9)

0%
- --------------------------------------------------------------------------------
12. Type of Reporting Person (See Instructions)

HC

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                                     Page 2

Item 1.

(a) Name of Issuer: Transgenomic, Inc.


(b) Address of Issuer's Principal Executive Offices:

12325 Emmet Street
Omaha NE68164



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Item 2.

(a) Name of Person Filing:   Barclays PLC

(b) Address of Principal Business Office or, if none, Residence:
                                                1 Churchill Place,
                                                London, E14 5HP, England

(c) Citizenship:   England

(d) Title of Class of Securities:   Common Stock

(e) CUSIP Number: 89365K206

- --------------------------------------------------------------------------------

Item 3.   If this statement is filed pursuant to Sub-Section 240.13d-1
          (b) or 240.13d-2(b)
          or (c), check whether the person filing is a:

(a) [ ] Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b) [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c) [ ] Insurance company as defined in section 3(a)(19) of the
        Act (15 U.S.C. 78c);
(d) [ ] Investment company registered under section 8 of the Investment
        Company Act of 1940 (15 U.S.C. 80a-8);
(e) [ ] An investment adviser in accordance with
        Sub-Section 240.13d-1(b)(1)(ii)(E);
(f) [ ] An employee benefit plan or endowment fund in accordance with
        Sub-Section 240.13d-1(b)(1)(ii)(F);
(g) [X] A parent holding company or control person in accordance with
        Sub-Section 240.13d-1(b)(1)(ii)(G);
(h) [ ] A savings association as defined in Section 3(b) of the
        Federal Deposit Insurance Act (12 U.S.C. 1813);
(i) [ ] A church plan that is excluded from the definition of an investment
        company under section 3(c)(14) of the Investment Company Act
        of 1940 (15 U.S.C. 80a-3);
(j) [ ] Group, in accordance with Sub-Section 240.13d-1(b)(1)(ii)(J).

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                                     Page 3

Item 4.   Ownership.

          Provide the following information regarding the aggregate number and
          percentage of the class of securities of the issuer identified in Item
          1.

(a) Amount beneficially owned: -0- shares

(b) Percent of class: 0%

(c) Number of shares as to which the person has:

     (i)    Sole power to vote or to direct the vote: -0-
     (ii)   Shared power to vote or to direct the vote: -0-.
     (iii)  Sole power to dispose or to direct the disposition of: -0-
     (iv)   Shared power to dispose or to direct the disposition of: -0-.
- --------------------------------------------------------------------------------

Item 5.   Ownership of Five Percent or Less of a Class.

          If this statement is being filed to report the fact that as of the
          date hereof the reporting person has ceased to be the beneficial owner
          of more than five percent of the class of securities, check the
          following

[X]
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Item 6.   Ownership of More than Five Percent on Behalf of Another Person.

          Not Applicable.
- --------------------------------------------------------------------------------

Item 7.   Identification and Classification of the Subsidiary Which Acquired the
          Security Being Reported on By the Parent Holding Company.

          See Exhibit A.
- --------------------------------------------------------------------------------

Item 8.   Identification and Classification of Members of the Group.

          Not Applicable.
- --------------------------------------------------------------------------------

Item 9.   Notice of Dissolution of Group.

          Not Applicable.
- --------------------------------------------------------------------------------

Item 10.  Certification.

          By signing below I certify that, to the best of my knowledge and
          belief, the securities referred to above were not acquired and are not
          held for the purpose of or with the effect of changing or influencing
          the control of the issuer of the securities and were not acquired and
          are not held in connection with or as a participant in any transaction
          having that purpose or effect.

                                     Page 4

SIGNATURE

          After reasonable inquiry and to the best of my knowledge and belief, I
          certify that the information set forth in this statement is true,
          complete and correct.

          Dated: February 14,2011

          By : Suzanne Rodway

          Title: Head of Compliance Operations

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INDEX TO EXHIBITS

Exhibit A     Item 7 Information

Exhibit B     Joint Filing Agreement




- --------------------------------------------------------------------------------

EXHIBIT A

     The Schedule 13G to which this attachment is appended is filed by Barclays
     PLC on behalf of itself and the following subsidiary:


Barclays Bank PLC.



- --------------------------------------------------------------------------------


EXHIBIT B

JOINT FILING AGREEMENT
The undersigned hereby agree that the Statement on Schedule 13G filed
herewith (and any amendments thereto), is being filed jointly with the
Securities and Exchange Commission pursuant to Rule 13d-1(k) (1) under the
Securities Exchange Act of 1934, as amended, on behalf of each such person.


Dated: February 14, 2011



BARCLAYS PLC
By:
Name: Suzanne Rodway

Title: Head of Compliance Operations




BARCLAYS BANK PLC.
By:
Name: Suzanne Rodway

Title: Head of Compliance Operations

                                     Page 5