-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, TtMvISIHaRiyjSYD1jaj933zPY++U2YDE1N1RtjBoTQ05CUN/WG1s7ideolVnt5D TLkVUYQcZstsFlq3i4XVgg== 0001047469-98-006340.txt : 19980218 0001047469-98-006340.hdr.sgml : 19980218 ACCESSION NUMBER: 0001047469-98-006340 CONFORMED SUBMISSION TYPE: SC 13G PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 19980217 SROS: NONE GROUP MEMBERS: CAP/HAMBRO,INC. GROUP MEMBERS: CAP/HAMBRO,L.P. GROUP MEMBERS: CROSS ATLANTIC PARTNERS K/S GROUP MEMBERS: CROSS ATLANTIC PARTNERS K/S II GROUP MEMBERS: CROSS ATLANTIC PARTNERS K/S III GROUP MEMBERS: HAMBRO AMERICA,INC. SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: GENE LOGIC INC CENTRAL INDEX KEY: 0001043914 STANDARD INDUSTRIAL CLASSIFICATION: SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731] IRS NUMBER: 061411336 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G SEC ACT: SEC FILE NUMBER: 005-53373 FILM NUMBER: 98540780 BUSINESS ADDRESS: STREET 1: 10150 OLD COLUMBIA RD CITY: COLUMBIA STATE: MD ZIP: 21046 BUSINESS PHONE: 4103093100 MAIL ADDRESS: STREET 1: 10150 OLD COLUMBIA RD CITY: COLUMBIA STATE: MD ZIP: 21046 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: CROSS ATLANTIC PARTNERS K/S CENTRAL INDEX KEY: 0001033799 STANDARD INDUSTRIAL CLASSIFICATION: [] FILING VALUES: FORM TYPE: SC 13G BUSINESS ADDRESS: STREET 1: HAMBRO INTERNATIONAL EQUITY PARTNERS STREET 2: 650 MADISON AVENUE CITY: NEW YORK STATE: NY ZIP: 10022 BUSINESS PHONE: 2122237400 SC 13G 1 SCHEDULE 13G-A OMB APPROVAL OMB Number: 3235-0145 Expires: October 31, 1998 Estimated average burden hours per response...14.90 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* ----- Gene Logic Inc. ---------------------------------- (Name of Issuer) Common Stock, $.01 par value ---------------------------------- (Title of Class of Securities) 0003686891 ---------------------------------- (CUSIP Number) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). (Continued on following page(s)) Page 1 of 16 Pages --- 13G Page 2 of 16 Pages --- --- - ------------------------------------------------------------------------------- (1) Name of Reporting Person S.S. or I.R.S. Identification No. of Above Person Cross Atlantic Partners K/S - ------------------------------------------------------------------------------- (2) Check the Appropriate Box if a Member (a) / / of a Group* (b) / / - ------------------------------------------------------------------------------- (3) SEC Use Only - ------------------------------------------------------------------------------- (4) Citizenship or Place of Organization Denmark - ------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Beneficially Power -0- Owned by -------------------------------------------------- Each Reporting (6) Shared Voting Person With Power 1,552,399 shares -------------------------------------------------- (7) Sole Dispositive Power -0- -------------------------------------------------- (8) Shared Dispositive Power 1,552,399 shares - ------------------------------------------------------------------------------- (9) Aggregate Amount Beneficially Owned by Each Reporting Person 1,552,399 shares - ------------------------------------------------------------------------------- (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares* / / - ------------------------------------------------------------------------------- (11) Percent of Class Represented by Amount in Row (9) 11.2% - ------------------------------------------------------------------------------- (12) Type of Reporting Person* PN - ------------------------------------------------------------------------------- 13G Page 3 of 16 Pages --- --- - ------------------------------------------------------------------------------- (1) Name of Reporting Person S.S. or I.R.S. Identification No. of Above Person Cross Atlantic Partners K/S II - ------------------------------------------------------------------------------- (2) Check the Appropriate Box if a Member (a) / / of a Group* (b) / / - ------------------------------------------------------------------------------- (3) SEC Use Only Denmark - ------------------------------------------------------------------------------- (4) Citizenship or Place of Organization - ------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Beneficially Power -0- Owned by -------------------------------------------------- Each Reporting (6) Shared Voting Person With Power 1,552,399 shares -------------------------------------------------- (7) Sole Dispositive Power -0- -------------------------------------------------- (8) Shared Dispositive Power 1,552,399 shares - ------------------------------------------------------------------------------- (9) Aggregate Amount Beneficially Owned by Each Reporting Person 1,552,399 shares - ------------------------------------------------------------------------------- (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares* / / - ------------------------------------------------------------------------------- (11) Percent of Class Represented by Amount in Row (9) 11.2% - ------------------------------------------------------------------------------- (12) Type of Reporting Person* PN - ------------------------------------------------------------------------------- 13G Page 4 of 16 Pages --- --- - ------------------------------------------------------------------------------- (1) Name of Reporting Person S.S. or I.R.S. Identification No. of Above Person Cross Atlantic Partners K/S III - ------------------------------------------------------------------------------- (2) Check the Appropriate Box if a Member (a) / / of a Group* (b) / / - ------------------------------------------------------------------------------- (3) SEC Use Only - ------------------------------------------------------------------------------- (4) Citizenship or Place of Organization Denmark - ------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Beneficially Power -0- Owned by -------------------------------------------------- Each Reporting (6) Shared Voting Person With Power 1,552,399 shares -------------------------------------------------- (7) Sole Dispositive Power -0- -------------------------------------------------- (8) Shared Dispositive Power 1,552,399 shares - ------------------------------------------------------------------------------- (9) Aggregate Amount Beneficially Owned by Each Reporting Person 1,552,399 shares - ------------------------------------------------------------------------------- (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares* / / - ------------------------------------------------------------------------------- (11) Percent of Class Represented by Amount in Row (9) 11.2% - ------------------------------------------------------------------------------- (12) Type of Reporting Person* PN - ------------------------------------------------------------------------------- 13G Page 5 of 16 Pages --- --- - ------------------------------------------------------------------------------- (1) Name of Reporting Person S.S. or I.R.S. Identification No. of Above Person CAP/Hambro, L.P. - ------------------------------------------------------------------------------- (2) Check the Appropriate Box if a Member (a) / / of a Group* (b) / / - ------------------------------------------------------------------------------- (3) SEC Use Only - ------------------------------------------------------------------------------- (4) Citizenship or Place of Organization Delaware - ------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Beneficially Power -0- Owned by -------------------------------------------------- Each Reporting (6) Shared Voting Person With Power 1,552,399 shares -------------------------------------------------- (7) Sole Dispositive Power -0- -------------------------------------------------- (8) Shared Dispositive Power 1,552,399 shares - ------------------------------------------------------------------------------- (9) Aggregate Amount Beneficially Owned by Each Reporting Person 1,552,399 shares - ------------------------------------------------------------------------------- (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares* / / - ------------------------------------------------------------------------------- (11) Percent of Class Represented by Amount in Row (9) 11.2% - ------------------------------------------------------------------------------- (12) Type of Reporting Person* PN - ------------------------------------------------------------------------------- 13G Page 6 of 16 Pages --- --- - ------------------------------------------------------------------------------- (1) Name of Reporting Person S.S. or I.R.S. Identification No. of Above Person CAP/Hambro, Inc. - ------------------------------------------------------------------------------- (2) Check the Appropriate Box if a Member (a) / / of a Group* (b) / / - ------------------------------------------------------------------------------- (3) SEC Use Only - ------------------------------------------------------------------------------- (4) Citizenship or Place of Organization Delaware - ------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Beneficially Power -0- Owned by -------------------------------------------------- Each Reporting (6) Shared Voting Person With Power 1,552,399 shares -------------------------------------------------- (7) Sole Dispositive Power -0- -------------------------------------------------- (8) Shared Dispositive Power 1,552,399 shares - ------------------------------------------------------------------------------- (9) Aggregate Amount Beneficially Owned by Each Reporting Person 1,552,399 shares - ------------------------------------------------------------------------------- (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares* / / - ------------------------------------------------------------------------------- (11) Percent of Class Represented by Amount in Row (9) 11.2% - ------------------------------------------------------------------------------- (12) Type of Reporting Person* CO - ------------------------------------------------------------------------------- 13G Page 7 of 16 Pages --- --- - ------------------------------------------------------------------------------- (1) Name of Reporting Person S.S. or I.R.S. Identification No. of Above Person Hambro America, Inc. - ------------------------------------------------------------------------------- (2) Check the Appropriate Box if a Member (a) / / of a Group* (b) / / - ------------------------------------------------------------------------------- (3) SEC Use Only - ------------------------------------------------------------------------------- (4) Citizenship or Place of Organization New York - ------------------------------------------------------------------------------- Number of Shares (5) Sole Voting Beneficially Power -0- Owned by -------------------------------------------------- Each Reporting (6) Shared Voting Person With Power 1,552,399 shares -------------------------------------------------- (7) Sole Dispositive Power -0- -------------------------------------------------- (8) Shared Dispositive Power 1,552,399 shares - ------------------------------------------------------------------------------- (9) Aggregate Amount Beneficially Owned by Each Reporting Person 1,552,399 shares - ------------------------------------------------------------------------------- (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares* / / - ------------------------------------------------------------------------------- (11) Percent of Class Represented by Amount in Row (9) 11.2% - ------------------------------------------------------------------------------- (12) Type of Reporting Person* CO - ------------------------------------------------------------------------------- Page 8 of 16 Pages --- --- NOTE: This statement on Schedule 13G is being filed on behalf of Cross Atlantic Partners K/S, Cross Atlantic Partners K/S II, Cross Atlantic Partners K/S III, CAP/Hambro, L.P., CAP/Hambro, Inc. and Hambro America, Inc. CAP/Hambro, L.P. is the sole general partner of Cross Atlantic Partners, K/S Cross Atlantic Partners K/S II, and Cross Atlantic Partners K/S III. CAP/Hambro, Inc. is the sole general partner of CAP/Hambro, L.P. Hambro America, Inc. is the sole shareholder of CAP/Hambro, Inc. ITEM 1(A). NAME OF ISSUER Gene Logic Inc. - ------------------------------------------------------------------------------- ITEM 1(B). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES 10150 Old Columbia Rd., Columbia, MD 21046 - ------------------------------------------------------------------------------- ITEM 2(A). NAME OF PERSON FILING Cross Atlantic Partners K/S, a Danish limited partnership - ------------------------------------------------------------------------------- ITEM 2(B). ADDRESS c/o Hambro Helath International, Inc. 650 Madison Avenue New York, NY 10022 - ------------------------------------------------------------------------------- ITEM 2(C). CITIZENSHIP OR PLACE OF ORGANIZATION Denmark - ------------------------------------------------------------------------------- ITEM 2(A). NAME OF PERSON FILING Cross Atlantic Partners K/S II, a Danish limited partnership - ------------------------------------------------------------------------------- ITEM 2(B). ADDRESS c/o Hambro Health International, Inc. 650 Madison Avenue New York, NY 10022 - ------------------------------------------------------------------------------- ITEM 2(C). CITIZENSHIP OR PLACE OF ORGANIZATION Denmark - ------------------------------------------------------------------------------- ITEM 2(A). NAME OF PERSON FILING Cross Atlantic Partners K/S III, a Danish limited partnership - ------------------------------------------------------------------------------- ITEM 2(B). ADDRESS c/o Hambro Health International, Inc. 650 Madison Avenue New York, NY 10022 - ------------------------------------------------------------------------------- ITEM 2(C). CITIZENSHIP OR PLACE OF ORGANIZATION Denmark - ------------------------------------------------------------------------------- ITEM 2(A). NAME OF PERSON FILING CAP/Hambro, L.P., the sole general partner of Cross Atlantic Partners K/S, Cross Atlantic Partners K/S II and Cross Atlantic Partners K/S III - ------------------------------------------------------------------------------- ITEM 2(B). ADDRESS c/o Hambro Health International, Inc. 650 Madison Avenue New York, NY 10022 - ------------------------------------------------------------------------------- ITEM 2(C). CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - ------------------------------------------------------------------------------- ITEM 2(A). NAME OF PERSON FILING CAP/Hambro, Inc., the sole general partner of CAP/Hambro, L.P., which is wholly-owned by Hambro America, Inc. - ------------------------------------------------------------------------------- ITEM 2(B). ADDRESS c/o Hambro Health International, Inc. 650 Madison Avenue New York, NY 10022 - ------------------------------------------------------------------------------- ITEM 2(C). CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - ------------------------------------------------------------------------------- ITEM 2(A). NAME OF PERSON FILING Hambro America, Inc., the parent corporation of CAP/Hambro, Inc. - ------------------------------------------------------------------------------- ITEM 2(B). ADDRESS c/o Hambro Health International, Inc. 650 Madison Avenue New York, NY 10022 - ------------------------------------------------------------------------------- ITEM 2(C). CITIZENSHIP OR PLACE OF ORGANIZATION New York - ------------------------------------------------------------------------------- ITEM 2(D). TITLE OF CLASS OF SECURITIES: Common Stock, $.01 par value. - ------------------------------------------------------------------------------- ITEM 2(E). CUSIP NUMBER 0003686891 - ------------------------------------------------------------------------------- ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULES 13D-1(B), OR 13D-2(B), CHECK WHETHER THE PERSON FILING IS A: Page 9 of 16 Pages --- --- (a) / / Broker or Dealer registered under Section 15 of the Act (b) / / Bank as defined in Section 3(a)(6) of the Securities Exchange Act of 1934 (the "Act"). (c) / / Insurance Company as defined in Section 3(a)(19) of the Act (d) / / Investment Company registered under Section 8 of the Investment Company Act of 1940. (e) / / Investment Adviser registered under Section 203 of the Investment Advisers Act of 1940 (f) / / Employee Benefit Plan, Pension Fund which is subject to the provisions of the Employee Retirement Income Security Act of 1974 or Endowment Fund; see Rule 13d-1(b)(1)(ii)(F) of the Act. (g) / / Parent Holding Company, in accordance with Rule 13d-1(b)(ii)(G) of the Act. (h) / / Group, in accordance with Rule 13d-1(b)(1)(ii)(H) of the Act. None of the above. ITEM 4. OWNERSHIP (a) Amount Beneficially Owned: As of December 31, 1997, each of the following is the owner of record of the number of shares of Common Stock set forth next to its name: Cross Atlantic Partners K/S 880,233 shares Cross Atlantic Partners K/S II 498,832 shares Cross Atlantic Partners K/S III 173,334 shares CAP/Hambro, L.P. 0 shares CAP/Hambro, Inc. 0 shares Hambro America, Inc. 0 shares Additionally, in its capacity as the sole general partner of Cross Atlantic Partners, K/S, Cross Atlantic Partners K/S II, and Cross Atlantic Partners K/S III, CAP/Hambro, L.P. is deemed to beneficially own an aggregate of 1,552,399 shares of Common Stock as of December 31, 1997. As CAP/Hambro, Inc. is the sole general partner of CAP/Hambro, L.P. and Hambro America, Inc. is the sole shareholder of CAP/Hambro, Inc., both of these entities are deemed to also beneficially own an aggregate of 1,552,399 shares of Common Stock as of December 31, 1997. - --------------------------------------------------------------------------- (b) Percent of Class: Cross Atlantic Partners K/S 11.2% Cross Atlantic Partners K/S II 11.2% Cross Atlantic Partners K/S III 11.2% CAP/Hambro, L.P. 11.2% CAP/Hambro, Inc. 11.2% Hambro America, Inc. 11.2% Page 10 of 16 Pages --- --- The foregoing percentages are calculated based on the 13,899,250 shares of Common Stock reported to be outstanding as of December 31, 1997 according to a representative from Gene Logic Inc. - ------------------------------------------------------------------------------- (c) Number of shares as to which such person has: (i) sole power to vote or to direct the vote: Cross Atlantic Partners K/S 0 shares Cross Atlantic Partners K/S II 0 shares Cross Atlantic Partners K/S III 0 shares CAP/Hambro, L.P. 0 shares CAP/Hambro, Inc. 0 shares Hambro America, Inc. 0 shares ----------------------------------------------------------------- (ii) shared power to vote or to direct the vote: Cross Atlantic Partners K/S 1,552,399 shares Cross Atlantic Partners K/S II 1,552,399 shares Cross Atlantic Partners K/S III 1,552,399 shares CAP/Hambro, L.P. 1,552,399 shares CAP/Hambro, Inc. 1,552,399 shares Hambro America, Inc. 1,552,399 shares ----------------------------------------------------------------- (iii) sole power to dispose or to direct the disposition of: Cross Atlantic Partners K/S 0 shares Cross Atlantic Partners K/S II 0 shares Cross Atlantic Partners K/S III 0 shares CAP/Hambro, L.P. 0 shares CAP/Hambro, Inc. 0 shares Hambro America, Inc. 0 shares ----------------------------------------------------------------- (iv) shared power to dispose or to direct the disposition of: Cross Atlantic Partners K/S 1,552,399 shares Cross Atlantic Partners K/S II 1,552,399 shares Cross Atlantic Partners K/S III 1,552,399 shares CAP/Hambro, L.P. 1,552,399 shares CAP/Hambro, Inc. 1,552,399 shares Hambro America, Inc. 1,552,399 shares Cross Atlantic Partners K/S, Cross Atlantic Partners K/S II, Cross Atlantic Partners K/S III, CAP/Hambro, L.P., CAP/Hambro, Inc., and Hambro America, Inc. expressly disclaim beneficial ownership of any shares of Common Stock of Gene Logic Inc., except any shares held directly of record. ----------------------------------------------------------------- ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following. / / Page 11 of 16 Pages --- --- ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON Not applicable. - ------------------------------------------------------------------------------- ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY Not applicable. - ------------------------------------------------------------------------------- ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP Not applicable. Cross Atlantic Partners K/S, Cross Atlantic Partners K/S II, Cross Atlantic Partners K/S III, CAP/Hambro, L.P., CAP/Hambro, Inc., and Hambro America, Inc. expressly disclaim membership in a "group" as defined in Rule 13d-1(b)(ii)(H). - ------------------------------------------------------------------------------- ITEM 9. NOTICE OF DISSOLUTION OF GROUP Not applicable. - ------------------------------------------------------------------------------- ITEM 10. CERTIFICATION Not applicable. This statement on Schedule 13G is not filed pursuant to Rule 13d-1(b). Attached as Exhibit 1 hereto is a Joint Filing Agreement executed by each of the filing persons pursuant to Rule 13d-1(f) under Section 13(d) of the Act. Page 12 of 16 Pages --- --- SIGNATURE After reasonable inquiry and to the best of his, her or its knowledge and belief, each of the undersigned certifies that the information set forth in this statement is true, complete and correct. We also hereby agree to file this statement jointly pursuant to the agreement set forth as Exhibit 1 hereto. Dated: February 13, 1998 CROSS ATLANTIC PARTNERS K/S By: CAP/HAMBRO, L.P. Its General Partner By: CAP/HAMBRO, INC. Its General Partner By: * ------------------------- Charles L. Dimmler, III Authorized Officer CROSS ATLANTIC PARTNERS K/S II By: CAP/HAMBRO, L.P. Its General Partner By: CAP/HAMBRO, INC. Its General Partner By: * ------------------------- Charles L. Dimmler, III Authorized Officer CROSS ATLANTIC PARTNERS K/S III By: CAP/HAMBRO, L.P. Its General Partner By: CAP/HAMBRO, INC. Its General Partner By: * ---------------------------- Charles L. Dimmler, III Authorized Officer Page 13 of 16 Pages --- --- CAP/HAMBRO, L.P. By: CAP/HAMBRO, INC. Its General Partner By: * ------------------------ Charles L. Dimmler, III Authorized Officer CAP/HAMBRO, INC. By: * ------------------------ David Barnett Authorized Officer HAMBRO AMERICA, INC. By: * ------------------------ David Barnett Authorized Officer *By: /s/ Lisa C. Torch ------------------------- Lisa C. Torch Attorney-in-fact - -------------------------------------------------------------------------------- - -------------------------------------------------------------------------------- * This Schedule 13G was executed by Lisa C. Torch pursuant to Powers of Attorney attached hereto as Exhibit 2. Exhibit 1 AGREEMENT Pursuant to Rule 13d-1(f) (1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13G need be filed with respect to the ownership by each of the undersigned of shares of Common Stock of Gene Logic Inc.. This Agreement may be executed in any number of counterparts, each of which shall be deemed an original. EXECUTED this 13th day of February, 1998. CROSS ATLANTIC PARTNERS K/S By: CAP/HAMBRO, L.P. Its General Partner By: CAP/HAMBRO, INC. Its General Partner By: * ----------------------- Charles L. Dimmler, III Authorized Officer CROSS ATLANTIC PARTNERS K/S II By: CAP/HAMBRO, L.P. Its General Partner By: CAP/HAMBRO, INC. Its General Partner By: * ----------------------- Charles L. Dimmler, III Authorized Officer CROSS ATLANTIC PARTNERS K/S III By: CAP/HAMBRO, L.P. Its General Partner By: CAP/HAMBRO, INC. Its General Partner By: * ----------------------- Charles L. Dimmler, III Authorized Officer CAP/HAMBRO, L.P. By: CAP/HAMBRO, INC. Its General Partner By: * ----------------------- Charles L. Dimmler, III Authorized Officer CAP/HAMBRO, INC. By: * ---------------------- David Barnett Authorized Officer HAMBRO AMERICA, INC. By: * ----------------------- David Barnett Authorized Officer *By: /s/ Lisa C. Torch --------------------- Lisa C. Torch Attorney-in-fact - -------------------------------------------------------------------------------- - -------------------------------------------------------------------------------- * This Agreement was executed by Lisa C. Torch pursuant to Powers of Attorney attached hereto as Exhibit 2. Exhibit 2 POWER OF ATTORNEY KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below hereby constitutes and appoints Edwin A. Goodman and Lisa C. Torch, and each of them, with full power to act without the other, his or her true and lawful attorney-in-fact, with full power of substitution, to sign any and all instruments, certificates and documents that may be necessary, desirable or appropriate to be executed on behalf of himself or herself as an individual or in his or her capacity as a general partner of, or an officer of a general partner of, CAP/Hambro, L.P., CAP/Hambro, Inc., Hambro America, Inc., Cross Atlantic Partners K/S, Cross Atlantic Partners K/S II and Cross Atlantic Partners K/S III, pursuant to Section 13 or 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and any and all regulations promulgated thereunder, and to file the same, with all exhibits thereto, and any other documents in connection therewith, with the Securities and Exchange Commission, and with any other entity when and if such is mandated by the Exchange Act or by the By-laws of the National Association of Securities Dealers, Inc., granting unto said attorney-in-fact full power and authority to do and perform each and every act and thing necessary, desirable or appropriate, fully to all intents and purposes as he or she might or could do in person, thereby ratifying and confirming all that said attorney-in-fact, or his substitutes, may lawfully do or cause to be done by virtue hereto. IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 13th day of February, 1998. /s/ John Cassis ---------------------------- John Cassis /s/ Charles L. Dimmler, III ---------------------------- Charles L. Dimmler, III /s/ David Barnett ---------------------------- David Barnett -----END PRIVACY-ENHANCED MESSAGE-----