EX-99.1 2 exhibit99-1.htm ANNUAL REPORT FOR THE YEAR ENDED DECEMBER 31, 2012 Exhibit 99.1

Exhibit 99.1


MESSAGE TO SHAREHOLDERS

Nymox is pleased to present its audited consolidated financial statements for its fiscal year ended December 31, 2012.

On February 21, 2012 Recordati and Nymox announced the start of activities aimed at the preparation of a European Phase III clinical trial for NX-1207, following the successful completion of a Scientific Advice meeting with the European Medicines Agency (EMA). The pivotal controlled clinical trial will assess the efficacy and safety of a single TRUS-guided intraprostatic injection of NX-1207 in patients with lower urinary tract symptoms (LUTS) associated with BPH not adequately controlled by medical therapy.

On March 1, 2012 Nymox announced the initiation of a Phase 2 U.S. clinical trial to evaluate the company’s NX-1207 drug for the treatment of low grade localized prostate cancer. The Company filed an Investigational New Drug (IND) application with the FDA. Clinical trial NX03-0040 will enroll 150 men in a two dose 6 week Phase 2 study designed in accordance with specific direction and guidance provided by the FDA in Pre-IND meetings. Preclinical studies of NX-1207 have shown activity against prostate cancer cells at higher dosage levels of NX-1207 than the dosage used in the current Phase 3 BPH clinical trials. The new study will test both low and high doses of NX-1207 for their effect on low grade localized prostate cancer.

On May 20, 2012 Nymox sponsored a symposium and panel discussion on NX-1207 held during the 2012 Annual Meeting of the American Urological Association in Atlanta, Georgia. The symposium, “Clinical studies of NX-1207: Phase 3 Injectable for BPH,” was chaired by Ronald Tutrone Jr, MD, FACS of Towson, MD, who has participated in three of the prospective NX-1207 clinical trials as well as follow-up studies. Dr. Tutrone presented an overview of NX-1207 and the NX-1207 clinical trials to date, including the two Phase 3 clinical trials currently in progress. Barton H. Wachs, MD, FACS, of Long Beach, CA, presented data from the new studies of the long-term efficacy of NX-1207 treatment. Mohamed Bidair, MD, FACS(C) of San Diego, CA, participated in the panel discussion in the symposium, along with Dr. Tutrone and Dr. Wachs. All symposium panelists are distinguished Board-certified urologists with extensive experience as clinical investigators in FDA-regulated clinical trials, including the NX-1207 clinical trials. A new research report was also presented, authored by Dr. Barton Wachs, Dr. Sheldon Freedman of Las Vegas, NV, Dr. Barrett Cowan of Denver, CO, and Dr. Neal Shore of Myrtle Beach, SC. The new data concerned outcome analyses of single-injection NX-1207 after 4 ½ years in 45 patients. Subjects in the NX-1207 2.5 mg cohort had mean improvements in their BPH symptoms that reached statistical significance (p < .0001). According to the report "NX-1207 is an office-based” procedure involving only a few minutes to administer associated with minimal discomfort and no catheter requirement,” and "results at 52-56 months after a single treatment indicate statistically significant symptomatic improvement and a very acceptable safety profile.”

On June 12, 2012 Nymox announced the first patient enrolment for the Phase 2 prostate cancer Study NX03-0040.

On July 11, 2012 Nymox announced the completion of enrollment for the Phase 3 repeat injection Study NX02-0020. The NX02-0020 study started in July 2011 and involved men who had previously participated in one of the earlier Nymox NX-1207 studies for benign prostatic hyperplasia (BPH). On September 18, Nymox announced positive results of the Safety Monitoring Committee review of safety data from the NX02-0020 repeat injection study. The Safety Monitoring Committee review was favorable and indicated no significant safety concerns for the trial to date.

On September 12, 2012 Nymox reported favorable results from the Safety Monitoring Committee review of ongoing safety data for the Company’s Phase 3 pivotal trials for NX-1207. The September 4, 2012 Safety Monitoring Committee meeting found no significant safety concerns to date.

On September 20, 2012 and on October 9, 2012, Nymox announced that the Independent Data Monitoring Committee for the Company's Phase 2 prostate cancer study (NX03-0040) had reported two positive analyses of safety data from the clinical trial. The Independent Data Monitoring Committee assessed patients who received high dose NX-1207 for treatment of their localized prostate cancer. The Independent Data Monitoring Committee is an arm's length independent body mandated to conduct periodic interim safety reviews at pre-determined stages during the study. The Committee has the authority to recommend changes to the study or to halt the study in the event of unacceptable drug toxicity. The Committee's interim safety analysis found no evidence of such toxicity and accordingly the study is continuing. The NX03-0040 study tests both low and high doses of NX-1207 for their effect on low grade localized prostate cancer. The NX-1207 dose is administered directly into the area of the prostate where the cancer was detected. The procedure is performed by a urologist in an office setting, does not require anaesthesia, sedation, or catheterization, takes only a few minutes and involves minimal discomfort to the patient. Patients in the study are randomly allocated to either low or high dose NX-1207 or to active surveillance (no treatment). Patients undergoing active surveillance in the trial also have the opportunity to receive NX-1207 after their trial active surveillance participation is completed.

1





Nymox reported positive new results from a follow-up study of patients who participated in the Company’s U.S. Study NX02-0016 of NX-1207 for the treatment of BPH completed in 2007. The follow-up study announced on March 26, 2012 assessed American Urological Association BPH Symptom Index scores and treatment outcomes in blinded subjects 52-56 months after a single initial injection of NX-1207 2.5 mg. No significant drug safety problems were reported by any subjects in the study initially as well as in the new long-term follow-up. The follow-up study found that of the patients who received NX-1207 2.5 mg, 52% were not currently taking BPH medication and had not received surgical treatments for their BPH; and 36% had required no medical or surgical treatments for their BPH since receiving their initial dose of NX-1207 2.5 mg. In the control group only one subject had not required any additional BPH treatments. The 36% of patients who received NX-1207 2.5 mg and did not require any other subsequent treatment for their BPH reported on average a 12.5 point improvement in their BPH symptom scores at 52-56 months; the 52% not currently taking BPH medication reported an average 10.0 point improvement. The level of symptomatic improvement for both NX-1207 2.5 mg cohorts reached statistical significance. In the initial NX02-0016 study’s Intent-to-Treat cohort after 90 days, patients treated with NX-1207 2.5 mg had a mean BPH Symptom Score improvement of 9.71 points, which was markedly better than the improvement shown by control groups (p<.001). The tested therapeutic dose of NX-1207 2.5 mg also reached statistical significance in Intent-to-Treat Primary Efficacy outcomes at 6 months post-treatment.

Nymox reported positive results from a new study of long-term treatment outcomes for men who had received a single injection of NX-1207 2.5 mg for treatment for their BPH. The study analysis reported on July 31, 2012 found that a statistically significant greater number of men who had received NX-1207 2.5 mg reported positive treatment outcomes as compared to men who had received a placebo. The study involved the latest available blinded follow-up study data (an average of 57 months post-injection) from the completed clinical trials for these treatment groups. A positive treatment outcome was seen if the patient was not using other BPH medications and no surgical treatment (including MIST) for BPH was reported at any time during the post-injection follow-up period. The combined new statistical analysis of blinded study data showed NX-1207 2.5 mg to have a lasting benefit in terms of positive treatment outcomes that was significantly superior to placebo (p=.02). Previous follow-up studies have shown long-term benefit from a single NX-1207 treatment in excess of 5 years in some cases.

On November 19, 2012, Nymox announced that recruitment will begin for NX02-0022, an open-label study of NX-1207. The study will enroll approximately 100-200 subjects who have already participated in previous studies of NX-1207. The study will assess the safety and efficacy of repeat injection of the drug. Eligible subjects will be enrolled from approximately 70 U.S. clinical trial sites.

On November 28, 2012, Nymox announced completion of patient enrollment in the Company’s pivotal U.S. Phase 3 NX02-0017 Study of NX-1207 for BPH. This study is now closed to further enrollment. Top-line results from the large Phase 3 Study are expected in late 2013.

Management and employees of Nymox wish to thank all of our shareholders for your important support. We look forward to exciting developments for your Company.



/s/ Paul Averback

Paul Averback MD
President

March 15, 2013

2





CORPORATE INFORMATION

Directors & Corporate Officers

Paul Averback MD, DABP - CEO, President and Chairman
Roy M. Wolvin - CFO
Jack Gemmell LLB - General Counsel and Director
Brian Doyle BSc, MBA - Senior Manager, Global Sales and Marketing
Randall Lanham Esq - Director
Paul McDonald - Director
Roger Guy MD - Director
Prof. David Morse PhD - Director
 
Auditors KPMG LLP
 
Legal Counsel Pillsbury Winthrop Shaw Pittman LLP
  Osler, Hoskin & Harcourt LLP
 
Transfer Agent Computershare Investor Services
 
Bankers BMO / Harris Bank
 
Stock Exchange Listings The NASDAQ Stock Market
 
Stock Trading Symbol NASDAQ : NYMX
 
Operating Facilities 777 Terrace Avenue
  Hasbrouck Heights, NJ, USA, 07604
 
  9900 Cavendish Blvd.
  St.-Laurent, PQ, Canada H4M 2V2
 
Website www.nymox.com
 
E-mail info@nymox.com

TABLE OF CONTENTS

Message to Shareholders 1
Corporate Information 3
Management's Discussion and Analysis 4
Management’s Report 15
Report of Independent Registered Public Accounting Firm 17
Report of Independent Registered Public Accounting Firm 18
Consolidated Statements of Financial Position 21
Consolidated Statements of Operations and Comprehensive Loss 22
Consolidated Statements of Changes in Equity 23
Consolidated Statements of Cash Flows 24
Notes to Consolidated Financial Statements 25

3





MANAGEMENT'S DISCUSSION AND ANALYSIS
(in US dollars)

This Management’s discussion and analysis (“MD&A”) comments on the Corporation’s operations, performance and financial condition as at and for the years ended December 31, 2012, 2011 and 2010. This MD&A should be read together with the audited Consolidated Financial Statements and the related notes. This MD&A is dated March 15, 2013. All amounts in this report are in U.S. dollars, unless otherwise noted.

Except as otherwise indicated, all financial information contained in this MD&A and in the Consolidated Financial Statements has been prepared in accordance with International Financial Reporting Standards (“IFRS”) as issued by the International Accounting Standards Board (“IASB”). The Consolidated Financial Statements and this MD&A were reviewed by the Corporation’s Audit and Finance Committee and were approved by our Board of Directors.

Additional information about the Corporation can be obtained on EDGAR at www.sec.gov or on SEDAR at www.sedar.com.

Overview

Corporate Profile

Nymox Pharmaceutical Corporation is a biopharmaceutical company with a significant R&D pipeline in development. Nymox is developing NX-1207, a novel treatment for benign prostatic hyperplasia which is in Phase 3 trials in the U.S. In December 2010, the Corporation signed a license and collaboration agreement with Recordati, a European pharmaceutical group, for the development and commercialization of NX-1207 in Europe including Russia and the CIS, the Middle East, the Maghreb area of North Africa and South Africa. The license and collaboration agreement covers the use of NX-1207 for the treatment of BPH as the initial indication for development and commercialization. NX-1207 showed positive results for the treatment of BPH in Phase 1 and 2 clinical trials in the U.S. and in follow-up studies of available subjects from the completed clinical trials. In June 2009, the Corporation began conducting the first of two pivotal double blind placebo controlled Phase 3 trials for NX-1207 that incorporate the specific protocol design recommendations provided to the Corporation by the FDA. The two pivotal Phase 3 studies for NX-1207 are being conducted at well-known investigational sites across the U.S. with planned enrollment of 1,000 patients. The first Phase 3 study, NX02-0017, completed enrollment in November 2012. An open-label U.S. re-injection safety study of NX-1207 for BPH was started in July of 2011 and reached completion of its primary endpoint assessment in January 2013. A Phase 2 study of NX-1207 for low grade localized prostate cancer was started in March 2012. The Corporation is also developing new treatments for bacterial infections in humans. Nymox has candidates which are under development as drug treatments aimed at the causes of Alzheimer’s disease, and has several other drug candidates in development. Nymox has U.S. and global patent rights for the use of statin drugs for the treatment and prevention of Alzheimer’s disease. Nymox developed the AlzheimAlert™ test, which is certified with a CE Mark in Europe. Nymox developed and markets NicAlert™ and TobacAlert™; which are tests that use urine or saliva to detect use of and exposure to tobacco products. NicAlert™ has received clearance from the FDA and is also certified with a CE Mark in Europe. TobacAlert™ is the first test of its kind to accurately measure second and third hand smoke exposure in individuals.

We have incurred operating losses throughout our history. Management believes that such operating losses will continue for at least the next few years. The costs relating to clinical trials for our potential therapeutic products will increase expenditures and delay profitability, despite anticipated increases in sales revenue in the coming years.

Risk Factors

The business activities of the Corporation since inception have been devoted principally to research and development. Accordingly, the Corporation has had limited revenues from sales and has not been profitable to date. We refer to the Risk Factors section of our Form 20-F filed on EDGAR and on SEDAR for a discussion of the management and investment issues that affect the Corporation and our industry. The risk factors that could have an impact on the Corporation’s financial results are summarized as follows:

  • Our Clinical Trials for Our Therapeutic Products in Development, Such as NX-1207, May Not be Successful and We May Not Receive the Required Regulatory Approvals Necessary to Commercialize These Products

  • Our Clinical Trials for Our Therapeutic Products, Such as NX-1207, May Be Delayed, Making it Impossible to Achieve Anticipated Development or Commercialization Timelines

  • A Setback in Any of Our Clinical Trials Would Likely Cause a Drop in the Price of our Shares

  • We May Not be Able to Make Adequate Arrangements with Third Parties for the Commercialization of our Product Candidates, such as NX-1207

  • We May Not Achieve our Projected Development Goals in the Time Frames We Announce and Expect

  • Even If We Obtain Regulatory Approvals for Our Product Candidates, We Will be Subject to Stringent Ongoing Government Regulation

  • It is Uncertain When, if Ever, We Will Make a Profit

4





  • We May Not Be Able to Raise Enough Capital to Develop and Market Our Products

  • We Face Challenges in Developing, Manufacturing and Improving Our Products

  • Our Products and Services May Not Receive Necessary Regulatory Approvals

  • We Face Significant and Growing Competition

  • We May Not Be Able to Successfully Market Our Products

  • Protecting Our Patents and Proprietary Information is Costly and Difficult

  • We Face Changing Market Conditions

  • Health Care Plans May Not Cover or Adequately Pay for Our Products and Services

  • We Are Subject to Continuing Potential Product Liability Risks, Which Could Cost Us Material Amounts of Money

  • The Issuance of New Shares May Dilute Nymox’s Stock

  • We Face Potential Losses Due to Foreign Currency Exchange Risks

  • We Have Never Paid a Dividend and are Unlikely to do so in the Foreseeable Future

Critical Accounting Policies

The consolidated financial statements of the Corporation have been prepared under International Financial Reporting Standards as issued by the International Accounting Standards Board. The Corporation’s functional and presentation currency is the United States dollar. Our accounting policies are described in the notes to our annual audited consolidated financial statements. We consider the following policies to be the most critical in understanding the judgments that are involved in preparing our financial statements and the matters that could impact our results of operations, financial condition and cash flows.

Revenue Recognition

The Corporation has generally derived its revenue from product sales and collaboration agreements. Revenue from product sales is recognized when the product has been delivered and obligations as defined in the agreement are performed. Collaboration agreements that include multiple deliverables are considered to be multiple-element arrangements. Under this type of arrangement, the identification of separate units of accounting is required and revenue is allocated among the separate units based on their relative fair values.

Payments received under a collaboration agreement may include upfront payments, milestone payments, sale of goods, royalties and license fees. Revenue for each unit of accounting are recorded as described below:

(i)     

Upfront payments:

Upfront payments are deferred and recognized as revenue on a systematic basis over the estimated service period. Changes in estimates are recognized prospectively when changes to the expected term are determined.

(ii)     

Milestone payments:

Revenue subject to the achievement of milestones is recognized only when the specified events have occurred and collectability is reasonably assured.

Specifically, the criteria for recognizing milestone payments are that (i) the milestone is substantive in nature, (ii) the achievement was not reasonably assured at the inception of the agreement, and (iii) the Corporation has no further involvement or obligation to perform associated with the achievement of the milestone, as defined in the related collaboration arrangement.

(iii)     

Sale of goods:

Revenue from the sale of goods is recognized when the Corporation has transferred to the buyer the significant risks and rewards of ownership of the goods, there is no continuing management involvement with the goods, and the amount of revenue can be measured reliably.

(iv)     

Royalties and license fees:

Royalties and license fees are recognized when conditions and events under the license agreement have occurred and collectability is reasonably assured.

Revenue recognition is subject to critical judgments, particularly in the collaboration agreement described above. Management uses judgment in estimating the service period over which revenue is recognized.

Valuation of Property and Equipment

Property and equipment are stated at cost and are amortized on a straight-line basis over the estimated useful lives. The Corporation reviews the unamortized balance of property and equipment, and recognizes any impairment in carrying value when it is identified. Factors we consider important, which could trigger an impairment review include:

5





  • Significant changes in the manner of our use of the acquired assets or the strategy for our overall business; and

  • Significant negative industry or economic trends.

The recoverable amount of an asset or cash-generating unit is the greater of its value in use and its fair value less costs to sell. In assessing value in use, the estimated future cash flows are discounted to their present value using a pre-tax discount rate that reflects current market assessments of the time value of money and the risks specific to the asset. For the purpose of impairment testing, assets that cannot be tested individually are grouped together into the smallest group of assets that generates cash inflows from continuing use that are largely independent of the cash inflows of other assets or groups of assets (the “cash-generating unit, or CGU”).

An impairment loss is recognized if the carrying amount of an asset or its CGU exceeds its estimated recoverable amount. Impairment losses recognized in respect of CGUs are allocated to reduce the carrying amounts of the assets in the CGU on a pro rata basis. Future events could cause management to conclude that impairment indicators exist and that the carrying values of the Corporation’s property and equipment are impaired.

Stock-based Compensation

Stock-based compensation is recorded using the fair value based method for stock options issued to employees and non-employees. Under this method, compensation cost related to employee awards is measured at fair value at the date of grant, net of forfeitures, and is expensed over the award’s vesting period. The Corporation uses the Black-Scholes options pricing model to calculate stock option values, which requires certain assumptions, including the future stock price volatility and expected time to exercise. There is estimation uncertainty with respect to selecting inputs to the Black-Scholes pricing model used to determine the fair value of the stock options. Changes to any of these assumptions, or the use of a different option pricing model, could produce different fair values for stock-based compensation, which could have a material impact on the Corporation’s earnings.

Recoverability of Deferred Tax Assets

Management judgment is required in assessing the recoverability of deferred tax assets. We have recorded no deferred tax assets as of December 31, 2012 and 2011, due to uncertainties related to our ability to utilize all, or a portion of, our deferred tax assets, primarily consisting of net operating losses carried forward and other unclaimed deductions, before they expire. In assessing the recoverability of deferred tax assets, management considers whether it is probable that some portion or all of the deferred tax assets will not be recovered. The ultimate recoverability of deferred tax assets is dependent upon the generation of future taxable income and tax planning strategies. The generation of future taxable income is dependent on the successful commercialization of the Corporation’s products and technologies.

Results of Operations

Selected Annual Information   2012      2011     2010   
Total revenues   $3,072,587     $3,113,815     $691,450  
Net loss   $(7,627,589 )   $(9,652,389 )   $(6,536,313 )
Loss per share (basic & diluted)   $(0.23 )   $(0.30 )   $(0.20 )
Total assets   $1,754,179     $6,375,266     $13,502,222  
Non-current financial liabilities   $400,000     $400,000     $400,000  

 

Quarterly Results   Q4 – 2012     Q3 – 2012     Q2 – 2012     Q1 – 2012  
Total revenues   $789,550     $764,564     $778,894     $739,579  
Net loss   $(2,813,922 )   $(1,245,563 )   $(1,721,128 )   $(1,846,974 )
Loss per share (basic & diluted)   $(0.08 )   $(0.04 )   $(0.05 )   $(0.06 )
     Q4 – 2011     Q3 – 2011     Q2 – 2011      Q1 – 2011  
Total revenues   $777,606     $804,712     $766,482     $765,015  
Net loss   $(1,659,125 )   $(1,614,041 )   $(1,948,132 )   $(4,431,091 )
Loss per share (basic & diluted)    $(0.05 )    $(0.05 )    $(0.06 )   $(0.14 )

The revenues in 2012 and 2011 include the recognition of revenue related to the upfront payment of €10 million (US$13.1 million) received from Recordati in December 2010.

Results of Operations – 2012 compared to 2011

Net losses were $2,813,922, or $0.08 per share, for the quarter, and $7,627,589, or $0.23 per share, for the year ended December 31, 2012, compared to $1,659,125, or $0.05 per share, for the quarter and $9,652,389, or $0.30 per share, for the year ended December 31, 2011. Net losses include stock compensation charges of $1,962,085 in 2012 and $4,005,404 in

6





2011. The decrease in net losses is principally attributable to the lower stock compensation charges recorded in 2012 compared to the same period in 2011. The weighted average number of common shares outstanding for the year ended December 31, 2012 was 33,176,185 compared to 32,711,431 for the same period in 2011.

Revenues

Revenues from sales of goods amounted to $135,150 for the quarter and $454,987 for the year ended December 31, 2012, compared with $123,206 for the quarter and $496,215 for the year ended December 31, 2011. A reduction in orders by one client for NicAlert™/TobacAlert™ explains the decrease in sales for 2012 compared to 2011. The development of therapeutic candidates and of moving therapeutic product candidates through clinical trials is a priority for the Corporation at this time. The growth of sales will become more of a priority once these candidates have reached the marketing stage. The Corporation expects that revenues will increase if and when product candidates pass clinical trials and are launched on the market.

For the three months and year ended December 31, 2012, amounts of $654,400 and $2,617,600 respectively were recognized as revenue relating to the upfront payment received from Recordati in December 2010, compared to $654,400 and $2,617,600 respectively for the three months and year ended December 31, 2011. At December 31, 2012, the deferred revenue related to this transaction recorded in the statement of financial position amounted to $7,743,733.

Research and Development

Research and development expenditures were $3,218,858 for the quarter and $8,572,528 for the year ended December 31, 2012, compared with $1,890,452 for the quarter and $9,461,081 for the year ended December 31, 2011. Research and development expenditures include costs incurred in advancing Nymox’s BPH product candidate NX-1207 through clinical trials, as well as costs related to its R&D pipeline in development. Research and development expenditures also include stock compensation charges of $1,653,428 for the quarter and $1,686,310 for the year ended December 31, 2012 and $32,042 for the quarter and $2,357,307 for the year ended December 31, 2011. Expenditures on the clinical trials for NX-1207 increased for the quarter compared to the same period in 2011 because of the initiation of new trials. The decrease in expenses for the year ended 2012 is primarily attributable to lower stock compensation charges compared to 2011. The balance of the decrease for the year is due to reductions in expenditures in 2012 relating to the initiation of new sites to the trials compared to the corresponding period in 2011. In 2012, research tax credits and grants amounted to $289,766 compared to $486,910 in 2011. The decrease is due to the recognition in 2011 of the grant awarded from the U.S. government under the Qualifying Therapeutic Discovery Project in the amount of $244,479, which was not repeated in 2012. The Corporation expects that research and development expenditures will decrease as product candidates finish development and clinical trials. However, because of the early stage of development of the Corporation’s R&D projects, it is impossible to outline the nature, timing or estimated costs of the efforts necessary to complete these projects, nor the anticipated completion dates for these projects. The facts and circumstances indicating the uncertainties that preclude us from making a reasonable estimate of the costs and timing necessary to complete projects include the risks inherent in any field trials, the uncertainty as to the nature and extent of regulatory requirements both for safety and efficacy, and the ability to manufacture the products in accordance with current good manufacturing requirements (cGMP) and in sufficient quantities both for large scale trials and for commercial use. A drug candidate that shows efficacy can take a long period (7 years or more) to achieve regulatory approval. There is also uncertainty whether we will be able to successfully adapt our patented technologies or whether any new products we develop will pass proof-of-principle testing both in the laboratory and in clinical trials, and whether we will be able to manufacture such products at a commercially competitive price. In addition, given the very high costs of development of therapeutic products, we anticipate having to partner with larger pharmaceutical companies to bring therapeutic products to market. The terms of such partnership arrangements along with our related financial obligations cannot be determined at this time and the timing of completion of the approval of such products will likely not be within our sole control.

Marketing Expenses

Marketing expenditures were $36,756 for the quarter and $158,431 for the year ended December 31, 2012, in comparison to expenditures of $51,964 for the quarter and $642,235 for the year ended December 31, 2011. Marketing expenditures also include stock compensation charges of $389 for the year ended December 31, 2012 and $434,635 in 2011. The decrease in expenses for the quarter and the year is primarily attributable to lower stock compensation charges in 2012 compared to 2011. The balance of the decrease for the year is due to a decrease in promotional expenses by approximately $51,000 in 2012 compared to 2011. The Corporation expects that marketing expenditures will increase if and when new products are launched on the market.

General and Administrative Expenses

General and administrative expenses were $356,341 for the quarter and $1,972,120 for the year ended December 31, 2012, compared with $443,895 for the quarter and $2,832,870 for the year ended December 31, 2011. General and administrative expenditures also include stock compensation charges of $275,386 for the year ended December 31, 2012 and $1,213,462 in 2011. The decrease in expenses for the quarter and the year is attributable to lower stock compensation charges in 2012 compared to 2011. The Corporation expects that general and administrative expenditures will increase as new product development leads to expanded operations.

7





Finance Costs - Foreign Exchange

The Corporation incurs expenses in the local currency of the countries in which it operates, which include the United States and Canada. Approximately 57% of 2012 expenses (2011 – 66%; 2010 – 78%) were in U.S. dollars. Foreign exchange fluctuations had no meaningful impact on the Corporation’s results in 2012, 2011 or 2010.

Inflation

The Corporation does not believe that inflation has had a significant impact on its results of operations.

Results of Operations – 2011 compared to 2010

Net losses were $1,659,125, or $0.05 per share, for the quarter, and $9,652,389, or $0.30 per share, for the year ended December 31, 2011, compared to $2,057,314, or $0.06 per share, for the quarter and $6,536,313, or $0.20 per share, for the year ended December 31, 2010. Net losses include stock compensation charges of $4,005,404 in 2011 and $478,865 in 2010. The increase in net losses in 2011 is principally attributable to the stock compensation charges. The weighted average number of common shares outstanding for the year ended December 31, 2011 was 32,711,431 compared to 31,940,584 for the same period in 2010.

Revenues

Revenues from sales of goods amounted to $123,206 for the quarter and $496,215 for the year ended December 31, 2011, compared with $204,076 for the quarter and $582,383 for the year ended December 31, 2010. A large number of orders by one client for NicAlert™/TobacAlert™ in 2010 were not repeated in 2011, which explains the decrease in sales.

For the three months and year ended December 31, 2011, amounts of $654,400 and $2,617,600 respectively were recognized as revenue relating to the upfront payment received from Recordati in December 2010, compared to $109,067 for the three months and year ended December 31, 2010. At December 31, 2011, the deferred revenue related to this transaction recorded in the statement of financial position amounted to $10,361,333.

Research and Development

Research and development expenditures were $1,890,452 for the quarter and $9,461,081 for the year ended December 31, 2011, compared with $1,396,699 for the quarter and $5,116,227 for the year ended December 31, 2010. Research and development expenditures include costs incurred in advancing Nymox’s BPH product candidate NX-1207 through clinical trials, as well as costs related to its R&D pipeline in development. Research and development expenditures also include stock compensation charges of $2,357,307 in the year ended December 31, 2011 and $318,184 in the comparative period in 2010. The increase in expenses in 2011 is primarily attributable to the stock compensation charges due to 905,000 options mainly granted in the first quarter of 2011 of which the majority vested immediately. Expenditures on the clinical trial for NX-1207 also increased compared to the same period in 2010, principally on salaries by approximately $353,000 and on clinical site and laboratory services by approximately $1,501,000, with corresponding increases for the quarter. In 2011, research tax credits and grants amounted to $486,910 compared to $236,101 in 2010 due to the recognition in 2011 of the grant awarded from the U.S. government under the Qualifying Therapeutic Discovery Project in the amount of $244,479.

Marketing Expenses

Marketing expenditures were $51,964 for the quarter and $642,235 for the year ended December 31, 2011, in comparison to expenditures of $42,589 for the quarter and $152,389 for the year ended December 31, 2010. Marketing expenditures also include stock compensation charges of $434,635 for the year ended December 31, 2011 and $4,780 in 2010. The increase in expenses in 2011 is primarily attributable to the stock compensation charges. The balance of the increase for the quarter and for the year is due to an increase in salaries by approximately $20,000 and costs of publicity by approximately $35,000 in 2011 compared to 2010.

General and Administrative Expenses

General and administrative expenses were $443,895 for the quarter and $2,832,870 for the year ended December 31, 2011, compared with $923,464 for the quarter and $1,847,122 for the year ended December 31, 2010. General and administrative expenditures also include stock compensation charges of $1,213,462 for the year ended December 31, 2011 and $155,901 in 2010. The increase in expenses in 2011 is attributable to the stock compensation charges. The decrease for the quarter is due to higher expenditures in the fourth quarter of 2010 in professional fees by approximately $780,000, which were not repeated in 2011.

8





Contractual Obligations

Nymox has no contractual obligations of significance other than long-term lease commitments for rental of laboratory and office space, insurance premium installments, other operating leases and redeemable preferred shares as follows:

Contractual Obligations   Total     Less than 1 year     1-3 years     4+ years  
Rent for laboratory and office space   $541,352     $355,837     $185,515     $0  
Insurance Premium Installments   $68,141     $68,141              
Operating Leases   $25,508      $10,595     $12,009     $2,904  
Total Contractual Obligations   $635,001     $434,573     $197,524     $2,904  

The redeemable preferred shares for the Corporation’s subsidiary Serex, Inc. in the amount of $400,000 have no specific terms of repayment.

Off-Balance Sheet Arrangements

The Corporation has no binding commitments for the purchase of property, equipment or intellectual property. The Corporation has no commitments that are not reflected in the statement of financial position except for operating leases and insurance premium installments.

Transactions with Related Parties

The Corporation had no transactions with related parties in 2012 and 2011.

Refer to note 18 of the consolidated financial statements for key management personnel disclosures.

Financial Position

Liquidity and Capital Resources

As of December 31, 2012, cash and receivables including tax credits totalled $1,030,075 and $617,099 respectively compared with $5,918,921 and $393,169 in the comparative period in 2011. In December 2010, the Corporation received an upfront payment of €10 million (US$13.1 million) pursuant to a license and collaboration agreement with Recordati for the development and commercialization of NX-1207 in Europe and other countries. The decrease in cash is primarily due to the use of this upfront payment. The increase in receivables is primarily due to timing of collection of research tax credits. In November 2011, the Corporation signed a common stock private purchase agreement, whereby Lorros-Greyse Investments, Ltd. (the “Purchaser”) was committed to purchase up to $15 million of the Corporation’s common shares over a twenty-four month period. The agreement became effective December 19, 2011. As at December 31, 2012, five drawings were made under this purchase agreement, for total proceeds of $3,575,000. On May 23, 2012, 132,100 common shares were issued at a price of $7.57 per share. On August 2, 2012, 88,087 common shares were issued at a price of $5.96 per share. On September 20, 2012, 95,652 common shares were issued at a price of $5.75 per share. On October 30, 2012, 82,781 common shares were issued at a price of $6.04 per share. On November 28, 2012, 160,000 common shares were issued at a price of $6.25 per share.

The Corporation negotiated a new agreement with the Purchaser on November 1, 2012, which became effective December 19, 2012, under the same terms and conditions of the previous agreement. The Corporation intends to access financing under this agreement when appropriate to fund its research and development. As at March 15, 2013, the Corporation had $14 million of financing available under the facility over the remaining 20 months under the agreement. The Corporation believes that cash balances, funds from operations, as well as funds from the common stock private purchase agreement will be sufficient to meet the Corporation’s cash requirements for the next twelve months.

The Corporation must comply with general covenants in order to draw on its facility including maintaining its stock exchange listing and registration requirements and having no material adverse effects, as defined in the agreement, with respect to the business and operations of the Corporation.

The Corporation relies primarily on this financing, and when applicable, collaboration agreements to fund its operations. In order to achieve the Corporation’s business plan and realization of its assets and liabilities in the normal course of operations, the Corporation anticipates the need to raise additional capital and/or achieve sales and other revenue generating activities.

Capital disclosures

The Corporation's objective in managing capital is to ensure a sufficient liquidity position to finance its research and development activities, general and administrative expenses, working capital and overall capital expenditures, including those

9





associated with patents. The Corporation makes every attempt to manage its liquidity to minimize shareholder dilution when possible.

The Corporation defines capital as total equity. To fund its activities, the Corporation has followed an approach that relies almost exclusively on the issuance of common shares and, during 2010, entered into a collaboration agreement. Since inception, the Corporation has financed its liquidity needs primarily through private placements and, since 2003, through a financing agreement with an investment company that has been replaced annually by a new agreement with the same purchaser (see note 9 (a) - Common Stock Private Purchase Agreement). The Corporation intends to access financing under this agreement when appropriate to fund its research and development activities. The financial crisis in the United States and the global economic environment has had a negative impact on the availability of liquidity in the market. Since 2003 through to December 2012, the Purchaser has always complied with the drawdowns made pursuant to the agreement. The Corporation believes that cash balances, funds from operations, as well as funds from the Common Stock Private Purchase Agreement will be sufficient to meet the Corporation’s cash requirements for the next twelve months.

The Corporation must comply with general covenants in order to draw on its facility including maintaining its stock exchange listing and registration requirements and having no material adverse effects, as defined in the agreement, with respect to the business and operations of the Corporation.

The capital management objectives remain the same as for the previous fiscal year. When possible, the Corporation tries to optimize its liquidity needs by non-dilutive sources, including sales, collaboration agreements, research tax credits and interest income. The Corporation's general policy on dividends is to retain cash to keep funds available to finance its research and development and operating expenses. The Corporation has no debt.

The Corporation is not subject to any capital requirements imposed by external parties.

Financial risk management

This section provides disclosures relating to the nature and extent of the Corporation’s exposure to risks arising from financial instruments, including foreign currency risk, credit risk, interest rate risk and liquidity risk, and to how the Corporation manages those risks.

Foreign currency risk

The Corporation uses the US dollar as its measurement currency because a substantial portion of revenues, expenses, assets and liabilities of its Canadian and US operations are denominated in US dollars. The Corporation’s equity financing facility is also in US dollars. Foreign currency risk is limited to the portion of the Corporation’s business transactions denominated in currencies other than the US dollar. The Canadian operation has transactions denominated in Canadian dollars, principally relating to salaries and rent. Additional variability arises from the translation of monetary assets and liabilities denominated in currencies other than the US dollar at each statement of financial position date. Fluctuations in the currency used for the payment of the Corporation’s expenses denominated in currencies other than the US dollar (primarily Canadian dollars) could cause unanticipated fluctuations in the Corporation’s operating results, but would not impair or enhance its ability to pay its Canadian dollar denominated obligations. The Corporation’s objective in managing its foreign currency risk is to minimize its net exposures to foreign currency cash flows by transacting with parties in US dollars to the maximum extent possible. The Corporation does not engage in the use of derivative financial instruments to manage its currency exposures.

Approximately 57% of expenses that occurred during the year ended December 31, 2012 (2011 - 66%; 2010 – 78%) were denominated in US dollars. Foreign exchange fluctuations had no meaningful impact on the Corporation’s results in 2012, 2011 or 2010.

The following table provides significant items exposed to foreign exchange:

CA$   December 31, 2012     December 31, 2011  
Cash   $167,006     $320,662  
Trade accounts receivable, other receivables and research tax credits receivable   $54,169     $119,192  
Trade accounts payable and accrued liabilities   $(389,256 )   $(399,802 )
    $(168,081 )   $40,052  

The following exchange rates were applied for the years ended December 31, 2012, 2011 and 2010:

 

Average rate (twelve months)

Reporting date rate

US$ - CA$ - December 31, 2012

0.9996

0.9949

US$ - CA$ - December 31, 2011

0.9891

1.0170

US$ - CA$ - December 31, 2010

1.0299

0.9946

10





Based on the Corporation’s foreign currency exposures noted above, varying the above foreign exchange rates to reflect a 5% strengthening of the US dollar would have increased the net loss for the year ended December 31, 2012 by less than $5,000, assuming that all other variables remained constant.

An assumed 5% weakening of the US dollar would have had an equal but opposite effect on the amount shown above, on the basis that all other variables remained constant.

Credit risk

Credit risk results from the possibility that a loss may occur from the failure of another party to perform according to the terms of the contract. Financial instruments that potentially subject the Corporation to concentrations of credit risk consist primarily of cash and trade accounts receivable. Cash is maintained with high-credit quality financial institutions. For trade accounts receivable, the Corporation performs periodic credit evaluations and typically does not require collateral. Allowances are maintained for potential credit losses consistent with the credit risk, historical trends, general economic conditions and other information.

The Corporation has a limited number of customers. Included in the consolidated statement of financial position are trade accounts receivable of $30,732 (December 31, 2011 - $31,546), all of which were aged under 45 days. Three customers (December 31, 2011 - four customers) accounted for 86.4% (December 31, 2011 - 100%) of the trade receivables balance at December 31, 2012, all of whom have a good payment record with the Corporation. No bad debt expense was recorded for the year ended December 31, 2012, nor for the year ended December 31, 2011.

At December 31, 2012, the Corporation’s maximum credit exposure corresponded to the carrying amount of cash, trade accounts receivable and other receivables.

Interest rate risk

Interest rate risk is the risk that the fair value or future cash flows of a financial instrument will fluctuate because of changes in market interest rates. Cash bears interest at a variable rate. Trade accounts receivable, other receivables, trade accounts payable and accrued liabilities bear no interest. The Corporation has no other interest-bearing financial instruments.

Based on the value of variable interest-bearing cash during the year ended December 31, 2012, an assumed 0.5% increase or 0.5% decrease in interest rates during such period would have had no significant effect on the net loss.

Liquidity risk

Liquidity risk is the risk that the Corporation will not be able to meet its financial obligations as they fall due. The Corporation manages liquidity risk through the management of its capital structure, as outlined in note 14 - Capital disclosures. The Corporation does not have an operating credit facility and finances its activities through an equity financing agreement with an investment company, as described in note 9 (a) - Common Stock Private Purchase Agreement.

The following are the contractual maturities of financial liabilities:

Trade accounts payable and accrued liabilities:   Carrying Amount     Less than 1 year     1 year to 5 years  
December 31, 2012   $1,055,159     $1,055,159      
December 31, 2011   $811,492     $811,492      

The redeemable preferred shares for the Corporation’s subsidiary Serex, Inc. in the amount of $400,000 have no specific terms of repayment.

Outstanding Share Data

As at March 15, 2013, there were 33,731,492 common shares of Nymox issued and outstanding. In addition, 5,930,500 share options are outstanding, of which 5,890,500 are currently vested. There are no warrants outstanding.

Subsequent Event

As at March 15, 2013, one drawing was made under the new common stock private purchase agreement, for total proceeds of $1,000,000. On February 4, 2013, 153,610 common shares were issued at a price of $6.51 per share.

Disclosure Controls and Procedures

Disclosure controls and procedures are designed to provide reasonable assurance that information required to be disclosed is accumulated and communicated to senior management on a timely basis so that appropriate decisions can be made

11





regarding public disclosure. The Corporation’s Chief Executive Officer and its Chief Financial Officer are responsible for establishing and maintaining disclosure controls and procedures. They are assisted in this responsibility by the Corporation’s disclosure committee, which is composed of members of senior management. Based on an evaluation of the Corporation’s disclosure controls and procedures, the Chief Executive Officer and Chief Financial Officer have concluded that the disclosure controls and procedures were effective as of December 31, 2012.

Internal Control over Financial Reporting

Management’s Annual Report on Internal Control Over Financial Reporting

Our management is responsible for establishing and maintaining adequate internal control over financial reporting. Our internal control over financial reporting includes those policies and procedures that: (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of our assets; (2) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally accepted accounting principles, and that our receipts and expenditures are being made only in accordance with authorizations of our management and directors; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use or disposition of our assets that could have a material effect on the financial statements.

Under the supervision and with the participation of our Chief Executive Officer and our Chief Financial Officer, management conducted an evaluation of the effectiveness of our internal control over financial reporting, as of December 31, 2012, based on the framework set forth in Internal Control-Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (COSO). Based on its evaluation under this framework, the Chief Executive Officer and the Chief Financial Officer concluded that our internal control over financial reporting was effective as of December 31, 2012.

Internal control over financial reporting has inherent limitations. Internal control over financial reporting is a process that involves human diligence and compliance and is subject to lapses in judgment and breakdowns resulting from human failures. Internal control over financial reporting also can be circumvented by collusion or improper management override. Because of such limitations, there is a risk that material misstatements may not be prevented or detected on a timely basis by internal control over financial reporting. However, these inherent limitations are known features of the financial reporting process. Therefore it is possible to design into the process safeguards to reduce, though not eliminate, this risk.

Attestation report of independent registered public accounting firm

KPMG LLP, an independent registered public accounting firm, which audited and reported on our financial statements in this Report to Shareholders, has issued an unqualified attestation report on the effectiveness of our internal control over financial reporting as at December 31, 2012.

Changes in Internal Controls Over Financial Reporting

There have been no changes during fiscal 2012 in our internal control over financial reporting that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

Changes in accounting policies:

New standards and interpretations issued but not yet adopted:

A number of new standards, interpretations and amendments to existing standards were issued by the IASB or International Financial Reporting Interpretations Committee (“IFRIC”). They are mandatory but not yet effective for the year ended December 31, 2012, and have not been applied in preparing these consolidated financial statements.

Many of these are not applicable or are inconsequential to the Corporation and have been excluded from the discussion below. The following standards and interpretations have been issued by the IASB and the IFRIC and the Corporation is currently assessing their impact on the financial statements:

IFRS 9 - Financial Instruments (“IFRS 9”) ultimately replaces IAS 39 - Financial Instruments: Recognition and Measurement (“IAS 39”). The replacement of IAS 39 is a three-phase project with the objective of improving and simplifying the reporting for financial instruments. The issuance of the first phase of the IFRS 9 provides guidance on the classification and measurement of financial assets and financial liabilities. IFRS 9 establishes two measurement categories for financial assets: amortized cost and fair value. Existing IAS 39 categories of loans and receivables, held-to-maturity investments, and available-for-sale financial assets have been eliminated. The criteria for a financial asset to be measured at amortized cost include: the objective of the business model is to hold assets in order to collect contractual cash flows; and, the contractual terms give rise, on contractual dates, to cash flows that are solely payments of principal and interest on principal outstanding. All other financial assets are measured at fair value.

12





The Company intends to adopt IFRS 9 in its consolidated financial statements for the annual period beginning on January 1, 2015. The Company has not yet assessed the impact of the adoption of this standard on its consolidated financial statements, however does not expect that it will have a significant impact.

IFRS 10 – Consolidated Financial Statements (”IFRS 10”) replaces SIC-12, Consolidation -Special Purpose Entities, and parts of IAS 27, Consolidated and Separate Financial Statements. The new standard builds on existing principles by identifying the concept of control as the determining factor in whether an entity should be included in a company’s consolidated financial statements. The standard provides additional guidance to assist in the determination of control where it is difficult to assess.

The Company intends to adopt IFRS 10, including the amendments issued in June 2012, in its consolidated financial statements for the annual period beginning on January 1, 2013. The Company does not expect IFRS 10 to have a significant impact on the consolidated financial statements.

IFRS 12 - Disclosure of Interests in Other Entities (“IFRS 12”) contains the disclosure requirements for entities that have interests in subsidiaries, joint arrangements (i.e. joint operations or joint ventures), associates and/or unconsolidated structured entities, aiming to provide information to enable users to evaluate:

  • the nature of, and risks associated with, an entity's interests in other entities; and

  • the effects of those interests on the entity's financial position, financial performance and cash flows.

The Company intends to adopt IFRS 12, including the amendments issued in June 2012, in its consolidated financial statements for the annual period beginning on January 1, 2013. The Company does not expect IFRS 12 to have a significant impact on the consolidated financial statements, because of the nature of the Company’s interests in other entities.

IFRS 13 - Fair Value Measurement (“IFRS 13”) provides new guidance on fair value measurement and disclosure requirements. IFRS 13 replaces the fair value measurement guidance contained in individual IFRS with a single source of fair value measurement guidance. It defines fair value, establishes a framework for measuring fair value and sets out disclosure requirements for fair value measurements. It explains how to measure fair value when it is required or permitted by other IFRS. It does not introduce new requirements to measure assets or liabilities at fair value, nor does it eliminate the practicability exceptions to fair value measurements that currently exist in certain standards.

The Company intends to adopt IFRS 13 prospectively in its consolidated financial statements for the annual period beginning on January 1, 2013. The Company does not expect IFRS 13 to have a significant impact on the consolidated financial statements.

Forward Looking Statements

Certain statements included in this MD&A may constitute “forward-looking statements” within the meaning of the U.S. Private Securities Litigation Reform Act of 1995 and Canadian securities legislation and regulations, and are subject to important risks, uncertainties and assumptions. This forward-looking information includes amongst others, information with respect to our objectives and the strategies to achieve these objectives, as well as information with respect to our beliefs, plans, expectations, anticipations, estimates and intentions. Forward-looking statements generally can be identified by the use of forward-looking terminology such as “may”, “will”, “expect”, “intend”, “estimate”, “anticipate”, “plan”, “foresee”, “believe” or “continue” or the negatives of these terms or variations of them or similar terminology. We refer you to the Corporation’s filings with the Canadian securities regulatory authorities and the U.S. Securities and Exchange Commission, as well as the “Risk Factors” section of this MD&A, and of our Form 20-F, for a discussion of the various factors that may affect the Corporation’s future results. The results or events predicted in such forward-looking information may differ materially from actual results or events.

Factors that could cause actual results or plans to differ materially from those projected in forward-looking statements made by, or on behalf of, the Corporation, many of which are beyond our control, include the Corporation’s ability to:

  • identify and capitalize on possible collaboration, strategic partnering or divestiture opportunities;

  • obtain suitable financing to support its operations and clinical trials;

  • manage its growth and the commercialization of its products;

  • achieve operating efficiencies as it progresses from a development-stage to a later-stage biotechnology corporation;

  • successfully compete in its markets;

  • realize the results it anticipates from the clinical trials of its products;

  • succeed in finding and retaining joint venture and collaboration partners to assist it in the successful marketing, distribution and commercialization of its products;

  • achieve regulatory clearances for its products;

13





  • obtain on commercially reasonable terms adequate product liability insurance for its commercialized products and avoid product liability claims;

  • adequately protect its proprietary information and technology from competitors and avoid infringement of proprietary information and technology of its competitors;

  • assure that its products, if successfully developed and commercialized following regulatory approval, are not rendered obsolete by products or technologies of competitors; and

  • not encounter problems with third parties, including key personnel, upon whom it is dependent.

Forward-looking statements do not take into account the effect that transactions or non-recurring or other special items announced or occurring after the statements are made have on the Corporation’s business. For example, they do not include the effect of business dispositions, acquisitions, other business transactions, asset writedowns or other charges announced or occurring after forward-looking statements are made. The financial impact of such transactions and non-recurring and other special items can be complex and necessarily depends on the facts particular to each of them.

We believe that the expectations represented by our forward-looking statements are reasonable, yet there can be no assurance that such expectations will prove to be correct. Furthermore, the forward-looking statements contained in this report are made as of the date of this report, and we do not undertake any obligation to update publicly or to revise any of the included forward-looking statements, whether as a result of new information, future events or otherwise unless required by applicable legislation or regulation. The forward-looking statements contained in this report are expressly qualified by this cautionary statement.

14





MANAGEMENT’S REPORT

The accompanying consolidated financial statements have been prepared by management and were approved by the Board of Directors of the Corporation. Management is responsible for the information and representations contained in these financial statements and other sections of this Annual Report. The financial statements have been prepared in accordance with International Financial Reporting Standards and its interpretations as issued by the International Accounting Standards Board. In preparing these consolidated financial statements, management selects appropriate accounting policies and uses its judgment and best estimates to report events and transactions as they occur. Management has determined such amounts on a reasonable basis in order to ensure that the financial statements are presented fairly, in all material respects. Financial data included throughout this Annual Report is prepared on a basis consistent with that of the financial statements.

To assist management in discharging these responsibilities, the Corporation maintains a system of internal controls which are designed to provide reasonable assurance that its assets are safeguarded, that transactions are executed in accordance with management’s authorization and that the financial records form a reliable base for the preparation of accurate and timely financial information.

KPMG LLP, the Corporation’s auditors, are appointed by the shareholders. Their audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, to enable them to express an opinion on the audited consolidated financial statements prepared in conformity with International Financial Reporting Standards as issued by the International Accounting Standards Board. In addition, our auditors have issued an attestation report on the effectiveness of the Corporation’s internal controls over financial reporting as of December 31, 2012.

The Board of Directors oversees management’s responsibilities for financial reporting and internal control. The Board exercises this responsibility through an Audit Committee composed of three independent Directors. The Audit Committee meets periodically with management and with the external auditors, to review audit recommendations and any matters, which the auditors believe, should be brought to the attention of the Board of Directors. The Audit Committee also reviews the consolidated financial statements and recommends to the Board of Directors that the statements be approved for issuance to the shareholders.



/s/ Paul Averback /s/ Roy Wolvin
 
Paul Averback Roy Wolvin
Chief Executive Officer & Chief Financial Officer &
President Secretary-Treasurer
 
March 15, 2013  

15





Consolidated Financial Statements of

NYMOX PHARMACEUTICAL
CORPORATION


As of December 31, 2012 and 2011, and for each of the years in the three-year period ended December 31, 2012

16





 
KPMG LLP Telephone (514) 840-2100
600 de Maisonneuve Blvd. West Fax (514) 840-2187
Suite 1500 Internet www.kpmg.ca
Tour KPMG    
Montréal, Québec H3A 0A3    

REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Shareholders and Directors of Nymox Pharmaceutical Corporation

We have audited the accompanying consolidated statements of financial position of Nymox Pharmaceutical Corporation as of December 31, 2012 and December 31, 2011 and the related consolidated statements of operations and comprehensive loss, changes in equity and cash flows for each of the years in the three-year period ended December 31, 2012. These consolidated financial statements are the responsibility of Nymox Pharmaceutical Corporation's management. Our responsibility is to express an opinion on these consolidated financial statements based on our audits.

We conducted our audits in accordance with Canadian generally accepted auditing standards and the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion.

In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the consolidated financial position of Nymox Pharmaceutical Corporation as of December 31, 2012 and 2011, and its consolidated financial performance and its consolidated cash flows for each of the years in the three-year period ended December 31, 2012 in conformity with International Financial Reporting Standards as issued by the International Accounting Standards Board.

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States), Nymox Pharmaceutical Corporation’s internal control over financial reporting as of December 31, 2012, based on the criteria established in Internal Control – Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (COSO), and our report dated March 1, 2013 expressed an unqualified opinion on the effectiveness of Nymox Pharmaceutical Corporation’s internal control over financial reporting.

/s/ KPMG LLP

March 1, 2013

Montréal, Canada

*CPA auditor, CA, public accountancy permit No. A120841
KPMG LLP is a Canadian limited liability partnership and a member firm of the KPMG
network of independent member firms affiliated with KPMG International Cooperative
(“KPMG International”), a Swiss entity.
KPMG Canada provides services to KPMG LLP.

17





 
KPMG LLP Telephone (514) 840-2100
600 de Maisonneuve Blvd. West Fax (514) 840-2187
Suite 1500 Internet www.kpmg.ca
Tour KPMG    
Montréal, Québec H3A 0A3    

REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Shareholders and Directors of Nymox Pharmaceutical Corporation

We have audited Nymox Pharmaceutical Corporation's internal control over financial reporting as at December 31, 2012, based on the criteria established in Internal Control - Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (COSO). Nymox Pharmaceutical Corporation's management is responsible for maintaining effective internal control over financial reporting and for its assessment of the effectiveness of internal control over financial reporting as presented in the section entitled “Management’s Annual Report on Internal Control over Financial Reporting” included in Management’s Discussion and Analysis. Our responsibility is to express an opinion on Nymox Pharmaceutical Corporation's internal control over financial reporting based on our audit.

We conducted our audit in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether effective internal control over financial reporting was maintained in all material respects. Our audit included obtaining an understanding of internal control over financial reporting, assessing the risk that a material weakness exists, and testing and evaluating the design and operating effectiveness of internal control based on the assessed risk. Our audit also included performing such other procedures as we considered necessary in the circumstances. We believe that our audit provides a reasonable basis for our opinion.

A company's internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles. A company's internal control over financial reporting includes those policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the company; (2) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally accepted accounting principles, and that receipts and expenditures of the company are being made only in accordance with authorizations of management and directors of the company; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company's assets that could have a material effect on the financial statements.

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.

 

KPMG LLP is a Canadian limited liability partnership and a member firm of the KPMG
network of independent member firms affiliated with KPMG International Cooperative
(“KPMG International”), a Swiss entity.
KPMG Canada provides services to KPMG LLP.

18






Page 2

 

In our opinion, Nymox Pharmaceutical Corporation maintained, in all material respects, effective internal control over financial reporting as of December 31, 2012, based on the criteria established in Internal Control - Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (COSO).

We also have audited, in accordance with Canadian generally accepted auditing standards and the standards of the Public Company Accounting Oversight Board (United States), the consolidated statements of financial position of Nymox Pharmaceutical Corporation as of December 31, 2012 and 2011 and the related consolidated statements of operations and comprehensive loss, changes in equity and cash flows for each of the years in the three year period ended December 31, 2012, and our report dated March 1, 2013 expressed an unqualified opinion on those consolidated financial statements.

/s/ KPMG LLP

March 1, 2013

Montréal, Canada

 

*CPA auditor, CA, public accountancy permit No. A120841

19





NYMOX PHARMACEUTICAL CORPORATION
Consolidated Financial Statements

As of December 31, 2012 and 2011, and for each of the years in the three-year period ended December 31, 2012

Financial Statements  
  Consolidated Statements of Financial Position 21
  Consolidated Statements of Operations and Comprehensive Loss 22
  Consolidated Statements of Changes in Equity 23
  Consolidated Statements of Cash Flows 24
Notes to Consolidated Financial Statements  
1. Business activities 25
2. Basis of preparation 25
3. Significant accounting policies 27
4. Changes in accounting policies 35
5. Property and equipment 38
6. Intangible assets 38
7. Licensing revenues and deferred revenue 39
8. Preferred shares of a subsidiary and non-controlling interest 39
9. Share capital 39
10. Commitments and contingencies 44
11. Cost of sales 45
12. Research tax credits and grants and income taxes 45
13. Earnings per share 49
14. Capital disclosures 49
15. Financial risk management 50
16. Financial instruments 53
17. Segment disclosures 53
18. Related parties 54
19. Personnel expenses 54
20. Subsequent events 54

20





NYMOX PHARMACEUTICAL CORPORATION
Consolidated Statements of Financial Position
 
December 31, 2012 and 2011
(In US dollars)

 

  Note   2012     2011  
 
Assets              
 
Current assets:              

Cash

  $ 1,030,075   $ 5,918,921  

Trade accounts receivable

    30,732     31,546  

Other receivables

    54,169     119,192  

Research tax credits receivable

    532,198     242,431  

Prepaid expenses

    31,988      

Security deposit

    17,396      

Inventories

    42,503     23,620  

Total current assets

    1,739,061     6,335,710  
Non-current assets:              

Long-term security deposit

        17,396  

Property and equipment

5   15,118     22,160  

Total non-current assets

    15,118     39,556  
Total assets   $ 1,754,179   $ 6,375,266  
 
Liabilities and Equity              
 
Current liabilities:              

Trade accounts payable

  $ 880,533   $ 640,507  

Accrued liabilities

             

Payroll related liabilities

    14,388     4,102  

Other accrued liabilities

    160,238     166,883  

Deferred revenue

7   2,617,600     2,617,600  

Total current liabilities

    3,672,759     3,429,092  
Non-current liabilities:              

Deferred revenue

7   5,126,133     7,743,733  

Preferred shares of a subsidiary

8   400,000     400,000  

Total non-current liabilities

    5,526,133     8,143,733  
Equity:              

Share capital

9   69,705,389     66,062,961  

Additional paid-in capital

    12,362,281     10,445,524  

Deficit

    (89,912,383 )   (82,106,044 )

Total equity attributable to the equity holders of the Corporation

    (7,844,713 )   (5,597,559 )
Non-controlling interest 8   400,000     400,000  
Total equity     (7,444,713 )   (5,197,559 )
Commitments and contingencies 10            
Total liabilities and equity   $ 1,754,179   $ 6,375,266  

See accompanying notes to consolidated financial statements.

On behalf of the Board:

/s/ Paul Averback, MD Director
 
/s/ Paul McDonald Director

21





NYMOX PHARMACEUTICAL CORPORATION
Consolidated Statements of Operations and Comprehensive Loss
 
Years ended December 31, 2012, 2011 and 2010
(In US dollars)

 

  Note   2012     2011     2010  
 
Revenues:                    
Sales of goods   $ 454,987   $ 496,215   $ 582,383  
Licensing Revenues:                    

Upfront payment

7   2,617,600     2,617,600     109,067  
      3,072,587     3,113,815     691,450  
 
Expenses:                    
Research and development 9(c)   8,572,528     9,461,081     5,116,227  
Less research tax credits 12(a)   (289,766 )   (486,910 )   (236,101 )
      8,282,762     8,974,171     4,880,126  
   
General and administrative 9(c)   1,972,120     2,832,870     1,847,122  
Marketing 9(c)   158,431     642,235     152,389  
Cost of sales 11   253,925     289,866     316,945  
      10,667,238     12,739,142     7,196,582  
Results from operating activities     (7,594,651 )   (9,625,327 )   (6,505,132 )
 
Net finance income (costs):                    

Finance income

16(b)   6,180     12,817     1,191  

Finance costs

16(b)   (39,118 )   (39,879 )   (32,372 )
      (32,938 )   (27,062 )   (31,181 )
                   
Net loss and comprehensive loss attributable to the equity holders of the Corporation   $ (7,627,589 ) $ (9,652,389 ) $ (6,536,313 )
 
Basic and diluted loss per share 13 $ (0.23 ) $ (0.30 ) $ (0.20 )
                     
Weighted average number of common shares outstanding 13   33,176,185     32,711,431     31,940,584  

See accompanying notes to consolidated financial statements.

22





NYMOX PHARMACEUTICAL CORPORATION
Consolidated Statements of Changes in Equity
 
Years ended December 31, 2012, 2011 and 2010
(In US dollars)

 

    Attributable to equity holders of the Corporation           
            Additional               Non-      
    Share capital paid-in                 controlling   Total  
  Note Number   Dollars   capital     Deficit     Total     interest   equity  
 
Balance, December 31, 2011   32,993,302 $ 66,062,961 $ 10,445,524   $ (82,106,044 ) $ (5,597,559 ) $ 400,000 $ (5,197,559 )
                                     

Transactions with owners, recorded directly in equity:

                                   

Issuance of share capital

9(a) 558,620   3,575,000           3,575,000       3,575,000  

Exercise of stock options and option surrender agreements

                                   

Cash

9(b) 20,520   22,100           22,100       22,100  

Ascribed value

    45,328   (45,328 )              

Share issue costs

          (178,750 )   (178,750 )     (178,750 )

Stock-based compensation

9(c)     1,962,085         1,962,085       1,962,085  
 
Total contributions by owners   579,140   3,642,428   1,916,757     (178,750 )   5,380,435       5,380,435  

 

Net loss and comprehensive loss

          (7,627,589 )   (7,627,589 )     (7,627,589 )
 
Balance, December 31, 2012   33,572,442 $ 69,705,389 $ 12,362,281   $ (89,912,383 ) $ (7,844,713 ) $ 400,000 $ (7,444,713 )
 
Balance, December 31, 2010   32,573,856 $ 62,855,147 $ 6,493,544   $ (72,203,305 ) $ (2,854,614 ) $ 400,000 $ (2,454,614 )
                                   

Transactions with owners, recorded directly in equity:

                                   

Issuance of share capital

9(a) 353,407   3,000,000           3,000,000       3,000,000  

Exercise of stock options and option surrender agreements

                                   

Cash

9(b) 66,039   54,040           54,040       54,040  

Ascribed value

    153,774   (53,424 )   (100,350 )          

Share issue costs

          (150,000 )   (150,000 )     (150,000 )

Stock-based compensation

9(c)     4,005,404         4,005,404       4,005,404  
 

Total contributions by owners

  419,446   3,207,814   3,951,980     (250,350 )   6,909,444       6,909,444  

 

                                   

Net loss and comprehensive loss

          (9,652,389 )   (9,652,389 )     (9,652,389 )
 
Balance, December 31, 2011   32,993,302 $ 66,062,961 $ 10,445,524   $ (82,106,044 ) $ (5,597,559 ) $ 400,000 $ (5,197,559 )
 
Balance, January 1, 2010   31,283,778 $ 57,955,147 $ 6,014,679   $ (65,421,992 ) $ (1,452,166 ) $ 400,000 $ (1,052,166 )
                                   

Transactions with owners, recorded directly in equity:

                                   

Issuance of share capital

9(a) 1,290,078   4,900,000           4,900,000       4,900,000  

Share issue costs

          (245,000 )   (245,000 )     (245,000 )

Stock-based compensation

9(c)     478,865         478,865       478,865  
 
Total contributions by owners   1,290,078   4,900,000   478,865     (245,000 )   5,133,865       5,133,865  
 
Net loss and comprehensive loss           (6,536,313 )   (6,536,313 )     (6,536,313 )
 
Balance, December 31, 2010   32,573,856 $ 62,855,147 $ 6,493,544   $ (72,203,305 ) $ (2,854,614 ) $ 400,000 $ (2,454,614 )

See accompanying notes to consolidated financial statements.

23





NYMOX PHARMACEUTICAL CORPORATION
Consolidated Statements of Cash Flows
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)

 

  Note 2012     2011     2010  
Cash flows from (used in) operating activities:                  

Net loss

$ (7,627,589 ) $ (9,652,389 ) $ (6,536,313 )

Adjustments for:

                 

Depreciation of property and equipment

5 10,413     14,716     10,223  

Stock-based compensation

9(c) 1,962,085     4,005,404     478,865  

Amortization of lease inducement

  -     -     (12,646 )

Changes in non-cash operating balances:

                 

Prepaid expenses

  (31,988 )   -     -  

Trade accounts receivable and other receivables

  65,837     (109,190 )   49,463  

Research tax credits receivable

  (289,767 )   (6,330 )   15,057  

Inventories

  (18,883 )   (6,172 )   18,966  

Long-term security deposit

  -     -     9,598  

Trade accounts payable and accrued liabilities

  243,667     (1,766,411 )   847,952  

Deferred revenue

  (2,617,600 )   (2,617,600 )   12,978,933  
    (8,303,825 )   (10,137,972 )   7,860,098  
 
Cash flows from (used in) financing activities:                  

Proceeds from issuance of share capital

9(a) 3,575,000     3,000,000     4,900,000  

Share issue costs

  (178,750 )   (150,000 )   (245,000 )

Proceeds from exercise of stock options

  22,100     54,040     -  
    3,418,350     2,904,040     4,655,000  
Cash flows used in investing activities:                  

Additions to property and equipment

  (3,371 )   (22,146 )   (8,801 )
Net (decrease) increase in cash   (4,888,846 )   (7,256,078 )   12,506,297  
 
Cash, beginning of year   5,918,921     13,174,999     668,702  
 
Cash, end of year $ 1,030,075   $ 5,918,921   $ 13,174,999  

See accompanying notes to consolidated financial statements.

24





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

1.     

Business activities:

Nymox Pharmaceutical Corporation is a company domiciled in Canada and is incorporated under the Canada Business Corporations Act. Nymox Pharmaceutical Corporation including its subsidiaries, Nymox Corporation, a Delaware Corporation, and Serex Inc. of New Jersey (together referred to as the “Corporation”), is a biopharmaceutical corporation, which specializes in the research and development of products for the aging population. The head-office of the Corporation is located at 9900 Cavendish Boulevard, Saint Laurent, Québec. The Corporation developed AlzheimAlertTM, a urinary test that aids physicians in the diagnosis of Alzheimer’s disease. The Corporation currently markets NicAlertTM and TobacAlertTM, tests that use urine or saliva to detect use of tobacco products. The Corporation is developing NX-1207, a novel treatment for benign prostatic hyperplasia which is in Phase 3 clinical trials. The Corporation is also developing therapeutics for the treatment of Alzheimer’s disease and new anti-bacterial agents for the treatment of bacterial infections in humans, including a treatment for E-coli O157:H7 bacterial contamination in meat and other food and drink products.

Since 1989, the Corporation’s activities and resources have been primarily focused on developing certain pharmaceutical technologies. The Corporation is subject to a number of risks, including the successful development and marketing of its technologies and maintaining access to existing financing arrangements under the Common Stock Private Purchase Agreement referred to in note 9 (a). The Corporation depends on this financing, as well as collaboration agreements, to fund its operations. In order to achieve its business plan and the realization of its assets and liabilities in the normal course of operations, the Corporation anticipates the need to raise additional capital and/or achieve sales and other revenue-generating activities. Management believes that cash balances, funds from operations, as well as funds from the common stock private purchase agreement will be sufficient to meet the Corporation's requirements for the next year.

The Corporation is listed on the NASDAQ Stock Market.

2.     

Basis of preparation:

 

(a)     

Statement of compliance:

The consolidated financial statements of the Corporation have been prepared in accordance with International Financial Reporting Standards (“IFRS”) and its interpretations as issued by the International Accounting Standards Board (“IASB”).

25





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

2.     

Basis of preparation (continued):

 

(a)     

Statement of compliance (continued):

The consolidated financial statements were authorized for issue by the Board of Directors on March 1, 2013.

(b)     

Basis of measurement:

The consolidated financial statements have been prepared on a going concern and on the historical cost basis.

(c)     

Functional and presentation currency:

These consolidated financial statements are presented in United States dollars, which is the Corporation and its subsidiaries’ functional currency.

(d)     

Use of estimates and judgments:

The preparation of the consolidated financial statements in conformity with IFRS requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, income and expenses.

Information about critical judgments in applying accounting policies and assumption and estimation uncertainties that have the most significant effect on the amounts recognized in the consolidated financial statements is noted below:

(i)     

Judgments in applying accounting policies

  • Licensing revenues and deferred revenue:

Revenue recognition is subject to critical judgments, particularly in collaboration agreements that include multiple deliverables, as judgment is required in allocating revenue to each component, including upfront payments, milestone payments, sale of goods, royalties and license fees. Management uses judgment in estimating the service period over which revenue is recognized (note 7).

(ii)     

Estimation uncertainties

  • Stock options:

There is estimation uncertainty with respect to selecting inputs to the Black-Scholes pricing model used to determine the fair value of the stock options (note 9 (c)).

Other areas of judgment and uncertainty relate to the recoverability of research tax credits and deferred tax assets.

Reported amounts and note disclosure reflect the overall economic conditions that are most likely to occur and anticipated measures management intends to take. Actual results could differ from those estimates.

The above estimates and assumptions are reviewed regularly. Revisions to accounting estimates are recognized in the period in which the estimates are revised and in any future periods affected.

26





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies:

The accounting policies set out below have been applied consistently to all periods presented in these consolidated financial statements. Refer to note 4 which addresses standards issued but not yet effective.

(a)     

Consolidation:

The consolidated financial statements of the Corporation have been prepared in accordance with IFRS and include the accounts of its subsidiaries. Subsidiaries are entities controlled by the Corporation. The financial statements of subsidiaries are included in the consolidated financial statements from the date that control commences until the date that control ceases. Intercompany balances and transactions have been eliminated on consolidation.

(b)     

Financial instruments:

Financial instruments are classified into one of the following five categories: held-for-trading, held-to-maturity investments, loans and receivables, available-for-sale financial assets or other financial liabilities. All financial instruments, including derivatives, are included in the consolidated statements of financial position and are measured at fair value, with the exception of loans and receivables, held-to-maturity investments and other financial liabilities, which are measured at amortized cost.

The Corporation has classified its cash, trade accounts receivable and other receivables as “loans and receivables”, and its trade accounts payable, accrued liabilities and redeemable preferred shares as “other financial liabilities”. The redeemable preferred shares are recorded at their redemption amount (see note 8).

The Corporation must classify the fair value measurements of financial instruments according to a three-level hierarchy, based on the type of inputs used in making these measurements. These tiers include: Level 1, defined as observable inputs such as quoted prices in active markets; Level 2, defined as inputs other than quoted prices in active markets that are either directly or indirectly observable; and Level 3, defined as unobservable inputs in which little or no market data exists, therefore requiring an entity to develop its own assumptions. As at December 31, 2012 and 2011, the Corporation held no assets or liabilities required to be measured at fair value.

(i)     

Financial assets:

The Corporation initially recognizes loans and receivables on the date that they are originated. Loans and receivables are financial assets with fixed or determinable payments that are not quoted in an active market. Such assets are recognized initially at fair value plus any directly attributable transaction costs. Subsequent to initial recognition, loans and receivables are measured at amortized cost using the effective interest method, less any impairment losses.

The Corporation derecognizes a financial asset when the contractual rights to the cash flows from the asset expire, or it transfers the rights to receive the contractual cash flows on the financial asset in a transaction in which substantially all the risks and rewards of ownership of the financial asset are transferred.

27





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies (continued):

 

(b)     

Financial instruments (continued):

 

(i)     

Financial assets (continued):

Financial assets and liabilities are offset and the net amount presented in the consolidated statements of financial position when, and only when, the Corporation has a legal right to offset the amounts and intends either to settle on a net basis or to realize the asset and settle the liability simultaneously.

(ii)     

Financial liabilities:

The Corporation initially recognizes other financial liabilities on the trade date at which the Corporation becomes a party to the contractual provisions of the instrument. Other financial liabilities are recognized initially at fair value plus any directly attributable transaction costs. Subsequent to initial recognition, these financial liabilities are measured at amortized cost using the effective interest method.

The Corporation derecognizes a financial liability when its contractual obligations are discharged, cancelled or expired.

Interest, losses and gains relating to a financial liability are recognized in the statement of operations and comprehensive loss.

(iii)     

Share capital:

Common shares are classified as equity. Incremental costs attributable to the issuance of common shares are recognized as an increase to deficit.

(c)     

Inventories:

Inventories consist of finished goods and are carried at the lower of first-in, first-out cost and net realizable value. Net realizable value is the estimated selling price in the ordinary course of business, less selling expenses.

(d)     

Property and equipment:

 

(i)     

Recognition and measurement:

Property and equipment are measured at cost, less accumulated depreciation and accumulated impairment losses. Cost includes expenditure that is directly attributable to the acquisition of the asset. Purchased software that is integral to the functionality of the related equipment is capitalized as part of that equipment. When parts of an item of property and equipment have significantly different useful lives, they are accounted for as separate items (major components) of property and equipment. Gains and losses on disposal of an item of property and equipment are recognized as the difference in the proceeds from disposal and the carrying amount of property and equipment.

28





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies (continued):

 

(d)     

Property and equipment (continued):

 

(ii)     

Subsequent costs:

The cost of replacing a part of an item of property and equipment is recognized in the carrying amount of the item if it is probable that the future economic benefits embodied within the part will flow to the Corporation, and its cost can be measured reliably. The carrying amount of the replaced part is derecognized. The costs of the day-to-day servicing of property and equipment are recognized in the statement of operations and comprehensive loss.

(iii)     

Depreciation:

Depreciation is calculated on the depreciable amount, which is the cost of an asset less its residual value. Depreciation is recognized on a straight-line basis over the estimated useful lives of each component of an item of property and equipment, since this most closely reflects the expected pattern of consumption of the future economic benefits embodied in the asset.

The estimated useful lives for the current and comparative periods are represented by the following estimated useful lives:

Asset Useful life
   
Laboratory equipment 5 years
Computer equipment 3 years
Office equipment and fixtures 5 years
   

Depreciation methods, useful lives and residual values are reviewed on an ongoing basis and adjusted if appropriate.

(e)     

Intangible assets:

 

(i)     

Intellectual property rights:

Intellectual property rights that are acquired by the Corporation and have finite useful lives are measured at cost less accumulated amortization and accumulated impairment losses.

29





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies (continued):

 

(e)     

Intangible assets (continued):

 

(ii)     

Research and development expenditures:

Expenditure on research activities, net of research tax credits, undertaken with the prospect of gaining new scientific or technical knowledge and understanding, is recognized in comprehensive loss as incurred. Development activities, net of research tax credits, involve a plan or design for the production of new or substantially improved products and processes. Development expenditure is capitalized only if development costs can be measured reliably, the product or process is technically and commercially feasible, future economic benefits are probable, and the Corporation intends to and has sufficient resources to complete development and to use or sell the asset. Other development expenditure is recognized in research and development expenses as incurred. At December 31, 2012 and December 31, 2011 no development expenditures have been capitalized.

(iii)     

Amortization:

Amortization is calculated on the cost of the asset, less its residual value. Amortization methods, useful lives and residual values are reviewed on an ongoing basis and adjusted if appropriate.

(f)     

Impairment:

 

(i)     

Financial assets:

Financial assets are assessed at each reporting date to determine whether there is objective evidence that they are impaired. A financial asset is impaired if objective evidence indicates that a loss event has occurred after the initial recognition of the asset, and that the loss event had a negative effect on the estimated future cash flows of that asset that can be estimated reliably. Objective evidence that financial assets are impaired can include default or delinquency by a debtor, restructuring of an amount due to the Corporation on terms that the Corporation would not consider otherwise, and indications that a debtor or issuer will enter bankruptcy.

In assessing impairment, the Corporation uses historical trends of the probability of default, timing of recoveries and the amount of loss incurred, adjusted for management’s judgment as to whether current economic and credit conditions are such that the actual losses are likely to be greater or less than suggested by historical trends.

30





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies (continued):

 

(f)     

Impairment (continued):

 

(i)     

Financial assets (continued):

An impairment loss in respect of a financial asset measured at amortized cost is calculated and recognized for the amount by which the asset's carrying amount exceeds the present value of the estimated future cash flows discounted at the asset’s original effective interest rate. Losses are reflected in an allowance account against receivables. When a subsequent event causes the amount of impairment loss to decrease, the decrease in impairment loss is reversed.

(ii)     

Non-financial assets:

The carrying amounts of the Corporation’s non-financial assets, including property and equipment, are reviewed at each reporting date to determine whether there is any indication of impairment. If any such indication exists, then the asset’s recoverable amount is estimated.

The recoverable amount of an asset or cash-generating unit is the greater of its value in use and its fair value less costs to sell. In assessing value in use, the estimated future cash flows are discounted to their present value using a pre-tax discount rate that reflects current market assessments of the time value of money and the risks specific to the asset. For the purpose of impairment testing, assets that cannot be tested individually are grouped together into the smallest group of assets that generates cash inflows from continuing use that are largely independent of the cash inflows of other assets or groups of assets (the “cash-generating unit, or CGU”).

The Corporation’s corporate assets do not generate separate cash inflows. If there is an indication that a corporate asset may be impaired, then the recoverable amount is determined for the CGU to which the corporate asset belongs.

An impairment loss is recognized if the carrying amount of an asset or its CGU exceeds its estimated recoverable amount. Impairment losses recognized in respect of CGUs are allocated to reduce the carrying amounts of the assets in the CGU on a pro rata basis.

Impairment losses recognized in prior periods are assessed at each reporting date for any indications that the loss has decreased or no longer exists. An impairment loss is reversed if there has been a change in the estimates used to determine the recoverable amount. An impairment loss is reversed only to the extent that the asset’s carrying amount does not exceed the carrying amount that would have been determined, net of depreciation or amortization, if no impairment loss had been recognized.

31





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies (continued):

 

(g)     

Revenue recognition:

Revenue from product sales is recognized when the product has been delivered and obligations as defined in the agreement are performed. Collaboration agreements that include multiple deliverables are considered to be multiple-element arrangements. Under this type of arrangement, the identification of separate units of accounting is required and revenue is allocated among the separate units based on their relative fair values.

Payments received under a collaboration agreement may include upfront payments, milestone payments, sale of goods, royalties and license fees. Revenue for each unit of accounting is recorded as described below:

(i)     

Upfront payments:

Upfront payments are deferred and recognized as revenue on a systematic basis over the estimated service period. Changes in estimates are recognized prospectively when changes to the expected term are determined.

(ii)     

Milestone payments:

Revenue subject to the achievement of milestones is recognized only when the specified events have occurred and collectability is reasonably assured.

Specifically, the criteria for recognizing milestone payments are that (i) the milestone is substantive in nature, (ii) the achievement was not reasonably assured at the inception of the agreement, and (iii) the Corporation has no further involvement or obligation to perform associated with the achievement of the milestone, as defined in the related collaboration arrangement.

(iii)     

Sale of goods:

Revenue from the sale of goods is recognized when the Corporation has transferred to the buyer the significant risks and rewards of ownership of the goods, there is no continuing management involvement with the goods, and the amount of revenue can be measured reliably.

(iv)     

Royalties and license fees:

Royalties and license fees are recognized when conditions and events under the license agreement have occurred and collectability is reasonably assured.

32





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies (continued):

 

(h)     

Foreign currency:

Monetary assets and liabilities of the Corporation’s Canadian and US subsidiaries denominated in currencies other than the US dollar are translated at the rates of exchange at the reporting date. Non-monetary items that are measured in terms of historical cost in a foreign currency are translated using the exchange rate at the date of the transaction. Income and expenses denominated in foreign currencies are translated at the average rate prevailing during the year.

Foreign exchange loss and gain are reported on a net basis, within finance costs or finance income.

(i)     

Research tax credits and grants:

The Corporation is entitled to scientific research and experimental development tax credits (“research tax credits”) granted by the Canadian federal government and the government of the province of Québec. Federal research tax credits, which are non-refundable, are earned on qualified research and development expenditures and can only be used to offset federal income taxes otherwise payable. Provincial research tax credits, which are refundable, are earned on qualified research and development expenditures incurred in the province of Québec.

The Corporation is also entitled to a grant from the U.S. Government under the Qualifying Therapeutic Discovery Project for its ongoing Phase III clinical trial program for NX-1207 for the treatment of benign prostatic hyperplasia of which, in April 2011, the Corporation received its full entitlement under this program.

These research tax credits and grants are recognized as a reduction of research and development expenditures in the period in which they become receivable, provided that there is reasonable assurance that they will be received.

(j)     

Stock-based compensation:

The grant date fair value of stock-based compensation awards granted to employees and directors is recognized as an expense, with a corresponding increase in equity, over the period that the employees or directors unconditionally become entitled to the awards. The amount recognized as an expense is adjusted to reflect the number of awards for which the related service vesting conditions are expected to be met, such that the amount ultimately recognized as an expense is based on the number of awards that do meet the related service at the vesting date.

33





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies (continued):

 

(k)     

Employee benefits:

Short-term employee benefits:

Short-term employee benefits obligations are measured on an undiscounted basis and are expensed as the related service is provided.

In addition to their salaries, employees of the Corporation are covered by a benefit package which includes a health plan, dental plan, disability insurance and life insurance coverage. Participation in this plan is paid by the Corporation in full. Any employee that elects to extend the coverage to members of their family must pay the additional premium.

(l)     

Lease payments:

Payments made under operating leases are recognized on a straight-line basis over the term of the lease. Lease incentives received are recognized as an integral part of the total lease expense, over the term of the lease.

(m)     

Income taxes:

Income tax expense comprises current and deferred taxes. Current tax and deferred tax are recognized in the statement of operations and comprehensive loss except to the extent that it relates to a business combination, or items recognized directly in equity or in other comprehensive loss.

Current tax is the expected tax payable or receivable on the taxable income or loss of the year, using tax rates enacted or substantively enacted at the reporting date, and any adjustment to tax payable in respect of previous years.

Deferred tax is recognized in respect of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for taxation purposes. Deferred tax is not recognized for the following temporary differences: the initial recognition of assets or liabilities in a transaction that is not a business combination and that affects neither accounting nor taxable profit or loss and differences relating to investments in subsidiaries to the extent that it is probable that they will not reverse in the foreseeable future. Deferred tax is measured at the tax rates that are expected to be applied to temporary differences when they reverse, based on the laws that have been enacted or substantively enacted by the reporting date. Deferred tax assets and liabilities are offset if there is a legally enforceable right to offset current tax liabilities and assets, and they relate to income taxes levied by the same tax authority on the same taxable entity, or on different tax entities, but they intend to settle current tax liabilities and assets on a net basis or their tax assets and liabilities will be realized simultaneously.

A deferred tax asset is recognized for unused tax losses and deductible temporary differences, to the extent that it is probable that future taxable profits will be available against which they can be utilized. Deferred tax assets are reviewed at each reporting date and are reduced to the extent that it is no longer probable that the related tax benefit will be realized.

34





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

3.     

Significant accounting policies (continued):

 

(n)     

Earnings per share:

Basic earnings per share are determined using the weighted average number of common shares outstanding during the period. Diluted earnings per share are computed in a manner consistent with basic earnings per share, except that the weighted average shares outstanding are increased to include additional shares from the assumed exercise of options and warrants, if dilutive. The number of additional shares is calculated by assuming that outstanding options were exercised, and that the proceeds from such exercises as well as the assumed proceeds from future services were used to acquire shares of common stock at the average market price during the reporting period.

(o)     

Determination of fair values:

Certain of the Corporation’s accounting policies and disclosures require the determination of fair value, for both financial and non-financial assets and liabilities. Fair values of stock options granted have been determined for measurement purposes based on the following method. When applicable, further information about the assumptions made in determining fair values is disclosed in the related notes.

Stock-based compensation:

The fair value of the stock options is measured using the Black-Scholes pricing model. Measurement inputs include share price on measurement date, exercise price of the instrument, expected volatility (based on weighted average historic volatility), weighted average expected life of the instruments (based on historical experience and general option holder behavior), expected dividends, and the risk-free interest rate (based on government bonds). Service conditions attached to the transactions are not taken into account in determining fair value.

(p)     

Segment reporting:

An operating segment is a component of the Corporation that engages in business activities from which it may earn revenues and incur expenses, including revenues and expenses that relate to transactions with any of the Corporation’s other components. Operating results of all operating segments are reviewed regularly by the Corporation’s Chief Executive Officer, who is the Corporation’s chief operating decision maker, who makes decisions about resources to be allocated to the segment and assesses its performance, and for which discrete financial information is available.

4.     

Changes in accounting policies:

New standards and interpretations issued but not yet adopted:

A number of new standards, interpretations and amendments to existing standards were issued by the IASB or International Financial Reporting Interpretations Committee (“IFRIC”). They are mandatory but not yet effective for the year ended December 31, 2012, and have not been applied in preparing these consolidated financial statements.

Many of these are not applicable or are inconsequential to the Corporation and have been excluded from the discussion below. The following standards and interpretations have been issued by the IASB and the IFRIC and the Corporation is currently assessing their impact on the financial statements:

35





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

4.     

Changes in accounting policies (continued):

New standards and interpretations issued but not yet adopted (continued):

IFRS 9 - Financial Instruments (“IFRS 9”) ultimately replaces IAS 39 - Financial Instruments: Recognition and Measurement (“IAS 39”). The replacement of IAS 39 is a three-phase project with the objective of improving and simplifying the reporting for financial instruments. The issuance of the first phase of the IFRS 9 provides guidance on the classification and measurement of financial assets and financial liabilities. IFRS 9 establishes two measurement categories for financial assets: amortized cost and fair value. Existing IAS 39 categories of loans and receivables, held-to-maturity investments, and available-for-sale financial assets have been eliminated. The criteria for a financial asset to be measured at amortized cost include: the objective of the business model is to hold assets in order to collect contractual cash flows; and, the contractual terms give rise, on contractual dates, to cash flows that are solely payments of principal and interest on principal outstanding. All other financial assets are measured at fair value.

The Company intends to adopt IFRS 9 in its consolidated financial statements for the annual period beginning on January 1, 2015. The Company has not yet assessed the impact of the adoption of this standard on its consolidated financial statements, however does not expect that it will have a significant impact.

IFRS 10 - Consolidated Financial Statements (”IFRS 10”) replaces SIC-12, Consolidation - Special Purpose Entities, and parts of IAS 27, Consolidated and Separate Financial Statements. The new standard builds on existing principles by identifying the concept of control as the determining factor in whether an entity should be included in a company’s consolidated financial statements. The standard provides additional guidance to assist in the determination of control where it is difficult to assess.

The Company intends to adopt IFRS 10, including the amendments issued in June 2012, in its consolidated financial statements for the annual period beginning on January 1, 2013. The Company does not expect IFRS 10 to have a significant impact on the consolidated financial statements.

IFRS 12 - Disclosure of Interests in Other Entities (“IFRS 12”) contains the disclosure requirements for entities that have interests in subsidiaries, joint arrangements (i.e. joint operations or joint ventures), associates and/or unconsolidated structured entities, aiming to provide information to enable users to evaluate:

  • the nature of, and risks associated with, an entity's interests in other entities; and

  • the effects of those interests on the entity's financial position, financial performance and cash flows.

The Company intends to adopt IFRS 12, including the amendments issued in June 2012, in its consolidated financial statements for the annual period beginning on January 1, 2013. The Company does not expect IFRS 12 to have a significant impact on the consolidated financial statements, because of the nature of the Company’s interests in other entities.

36





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

4.     

Changes in accounting policies (continued):

New standards and interpretations issued but not yet adopted (continued):

IFRS 13 - Fair Value Measurement (“IFRS 13”) provides new guidance on fair value measurement and disclosure requirements. IFRS 13 replaces the fair value measurement guidance contained in individual IFRS with a single source of fair value measurement guidance. It defines fair value, establishes a framework for measuring fair value and sets out disclosure requirements for fair value measurements. It explains how to measure fair value when it is required or permitted by other IFRS. It does not introduce new requirements to measure assets or liabilities at fair value, nor does it eliminate the practicability exceptions to fair value measurements that currently exist in certain standards.

The Company intends to adopt IFRS 13 prospectively in its consolidated financial statements for the annual period beginning on January 1, 2013. The Company does not expect IFRS 13 to have a significant impact on the consolidated financial statements.

37





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

5.     

Property and equipment:

 
                Office        
                equipment        
    Laboratory     Computer     and        
    equipment     equipment     fixtures     Total  
 
Cost:                        

Balance at December 31, 2010

$ 433,201   $ 22,597   $ 92,767   $ 548,565  

Additions

  2,907     9,651     9,588     22,146  

Disposals

      (1,600 )   (429 )   (2,029 )
 

Balance at December 31, 2011

$ 436,108   $ 30,648   $ 101,926   $ 568,682  
 

Balance at December 31, 2011

$ 436,108   $ 30,648   $ 101,926   $ 568,682  

Additions

  3,003     368         3,371  

Disposals

  (20,684 )   (1,790 )   (690 )   (23,164 )
 

Balance at December 31, 2012

$ 418,427   $ 29,226   $ 101,236   $ 548,889  
 
Accumulated depreciation:                        

Balance at December 31, 2010

$ 428,008   $ 16,599   $ 89,228   $ 533,835  

Depreciation for the year

  5,521     6,018     3,177     14,716  

Disposals

      (1,600 )   (429 )   (2,029 )
 

Balance at December 31, 2011

$ 433,529   $ 21,017   $ 91,976   $ 546,522  
 

Balance at December 31, 2011

$ 433,529   $ 21,017   $ 91,976   $ 546,522  

Depreciation for the year

  1,717     5,518     3,178     10,413  

Disposals

  (20,684 )   (1,790 )   (690 )   (23,164 )
 

Balance at December 31, 2012

$ 414,562   $ 24,745   $ 94,464   $ 533,771  
 
Carrying amounts:                        

At December 31, 2010

$ 5,193   $ 5,998   $ 3,539   $ 14,730  

At December 31, 2011

  2,579     9,631     9,950     22,160  

At December 31, 2012

  3,865     4,481     6,772     15,118  

 

                       

The depreciation expense of property and equipment is included in research and development in the statements of operations and comprehensive loss.

6.     

Intangible assets:

The intellectual property rights, having a cost of $2,222,661 and an accumulated amortization of $2,222,661 at December 31, 2011 and 2012, are still property of the Corporation.

38





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

7.     

Licensing revenues and deferred revenue:

On December 16, 2010, the Corporation signed a license and collaboration agreement with Recordati Ireland Ltd. (“Recordati”), a European pharmaceutical group, for the development and commercialization of NX-1207 in Europe, including Russia and the CIS, the Middle East, the Maghreb area of North Africa and South Africa. The license and collaboration agreement covers the use of NX-1207 for the treatment of benign prostatic hyperplasia (“BPH”) as the initial indication for development and commercialization. Recordati made an upfront payment to the Corporation of €10 million (US$13,088,000), in December 2010. The agreement provides for further payments to be made upon regulatory approval and sales milestones payments, and tiered supply and royalty payments of a minimum of 26% to increase progressively up to 40% of total net sales in the case specific contractual conditions are achieved.

The upfront payment of $13,088,000 has been deferred and is being recognized as revenue on a systematic basis over the estimated service period of five years, of which approximately three years remain at December 31, 2012. This period may be modified in the future based on additional information that may be received by the Corporation. In 2012, an amount of $2,617,600 (2011 - $2,617,600; 2010 - $109,067) was recognized as revenue related to this upfront payment. As at December 31, 2012, the deferred revenue related to this transaction amounted to $7,743,733 (2011 - $10,361,333).

8.     

Preferred shares of a subsidiary and non-controlling interest:

The preferred shares of a subsidiary and the non-controlling interest relate to redeemable and/or convertible preferred shares of Serex in the amount of $800,000. These preferred shares are convertible into common shares of Serex at a price of $3.946 per share. Up to 50% of the preferred shares are redeemable at any time at the option of the preferred shareholders for their issue price, subject to holders with at least 51% of the face value of the preferred shares asking for redemption, and sufficient funds being available in Serex. These redeemable preferred shares in the amount of $400,000 have been presented as a liability in the statements of financial position and are measured at their issue price which is also the redemption value. The non-redeemable portion is presented within equity, separately from equity of the owners of the Corporation, as non-controlling interest.

9.     

Share capital:

    2012   2011   
 
Authorized:        

An unlimited number of common shares, at no par value

       
         
Issued, outstanding and fully paid:        

Number of common shares

  33,572,442   32,993,302

Dollars

$ 69,705,389 $ 66,062,961  
           

39





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

9.     

Share capital (continued):

The holders of common shares are entitled to receive dividends as declared, which is at the discretion of the Corporation, and are entitled to one vote per share at the annual general meeting of the Corporation. The Corporation has never paid any dividends.

(a)     

Common Stock Private Purchase Agreement:

In November 2011, the Corporation entered into a Common Stock Private Purchase Agreement with an investment company (the "Purchaser") that established the terms and conditions for the purchase of common shares by the Purchaser. In November 2012, this agreement was terminated and a new agreement was concluded with the Purchaser. In general, the Corporation can, at its discretion, require the Purchaser to purchase up to $15 million of common shares over a 24-month period based on notices given by the Corporation. The Corporation must comply with general covenants in order to draw on its facility, including maintaining its stock exchange listing and registration requirements and having no material adverse effects, as defined in the agreement, with respect to the business and operations of the Corporation.

The number of shares to be issued in connection with each notice shall be equal to the amount specified in the notice, divided by 97% of the average price of the Corporation's common shares for the five days preceding the giving of the notice. The maximum amount of each notice is $1,000,000 and the minimum amount is $100,000. The Corporation may terminate the agreement before the 24-month term, if it has issued at least $8 million of common shares under the agreement.

In 2012, the Corporation issued 558,620 (2011 - 353,407; 2010 – 1,290,078) common shares to the Purchaser for aggregate proceeds of $3,575,000 (2011 - $3,000,000; 2010 - $4,900,000) under the agreements. All issued shares were fully paid. At December 31, 2012, the Corporation can require the Purchaser to purchase up to $15,000,000 of common shares over the remaining 22 months of the agreement, provided the Corporation adheres to its covenants.

The Corporation records the equity transaction at the amount received.

40





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

9.     

Share capital (continued):

 

(b)     

Stock options:

The Corporation has established a stock option plan (the “Plan”) for its key employees, its officers and directors, and certain consultants. The Plan is administered by the Board of Directors of the Corporation. The Board may from time to time designate individuals to whom options to purchase common shares of the Corporation may be granted, the number of shares to be optioned to each, and the option price per share. The option price per share cannot involve a discount to the market price at the time the option is granted. On June 13, 2011, the shareholders approved a resolution to increase the maximum number of shares which may be optioned under the stock option plan from 5,500,000 to 7,500,000. The maximum number of shares which may be optioned to any one individual is 15% of the total issued and outstanding common shares. Options under the Plan expire ten years after the grant and vest either immediately or over periods of up to six years, and are equity-settled. As at December 31, 2012, 1,559,500 options could still be granted by the Corporation (2011 - 2,121,500; 2010 – 886,000).

41





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

9.     

Share capital (continued):

 

(b)     

Stock options (continued):

The following table provides the activity of stock option awards during the year and for options outstanding and exercisable at the end of the year, the weighted average exercise price, and the weighted average years to expiration.

        Options outstanding        
          Weighted
        Weighted average
        average remaining
        exercise contractual
  Number     price     life (in years)  
       
Outstanding,          

January 1, 2010

4,724,000    $ 3.07       6.24   
 
Granted 65,000     3.09  
Expired (175,000 )   3.13        
   
Outstanding,                  

December 31, 2010

4,614,000   $ 3.06       5.32   
 
Exercised (28,000 )   1.93  
Granted 905,000     7.10  
Expired (2,500 )   3.57  
Surrendered (110,000 )   3.83        
   
Outstanding,                 

December 31, 2011

5,378,500   $ 3.73     5.22  
 
Exercised (8,000 )   2.76  
Granted 590,000     6.66  
Surrendered (20,000 )   2.89        
   
Outstanding,                  

December 31, 2012

5,940,500   $ 4.03     4.74  
 
Options exercisable 5,885,500   $ 4.00     4.72  

The weighted average share price at the date of exercise for stock options exercised in 2012 was $7.03 (2011 - $7.48; 2010 - no stock options exercised).

In 2012, a total of 20,000 options were surrendered (i.e. a “cashless exercise”) to the Corporation (2011 - 110,000; 2010 - nil) in consideration for the issuance of a total of 12,520 common shares (2011 - 38,039; 2010 - nil), whereby the option holders receive a number of shares equivalent in value to the net difference between the strike price on the option and the closing market price on the day before the date of the cashless exercise.

42





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

9.     

Share capital (continued):

   

(b)     

Stock options (continued):

At December 31, 2012, options outstanding and exercisable were as follows:

Options outstanding Options exercisable Exercise price per share Expiry date
 
50,000 50,000 $ 3.75 April 28, 2013
21,000 21,000 2.62 September 9, 2013
500,000 500,000 3.00 October 24, 2013
175,000 175,000 2.82 June 9, 2016
30,000 30,000 2.74 July 17, 2016
3,412,500 3,412,500 3.00 August 24, 2016
40,000 40,000 5.95 August 23, 2017
40,000 40,000 3.61 July 16, 2018
50,000 50,000 3.30 January 23, 2019
2,000 2,000 3.05 March 24, 2019
20,000 20,000 3.65 May 14, 2019
40,000 40,000 4.83 July 9, 2019
25,000 25,000 3.40 May 3, 2020
40,000 40,000 2.90 July 16, 2020
790,000 790,000 7.08 January 24, 2021
75,000 60,000 6.27 March 16, 2021
40,000 40,000 9.10 July 16, 2021
50,000 10,000 8.04 April 1, 2018
40,000 40,000 6.88 July 16, 2022
500,000 500,000 6.51 October 15, 2022
       
5,940,500 5,885,500 $ 4.03  

 

(c)     

Stock-based compensation:

   
    2012   2011   2010  
Stock options granted in 2006 $ 29,488 $ 184,490 $ 361,160
Stock options granted in 2010   -   -   117,705
Stock options granted in 2011   46,242   3,820,914   -
Stock options granted in 2012   1,886,355   -   -   
Total stock-based compensation expense recognized $ 1,962,085 $ 4,005,404 $ 478,865   

The stock-based compensation expense is disaggregated in the statements of operations and comprehensive loss as follows:

    2012   2011   2010  
Stock-based compensation pertaining to general and administrative $ 275,386 $ 1,213,462 $ 155,901
Stock-based compensation pertaining to marketing   389   434,635   4,780
Stock-based compensation pertaining to research and development   1,686,310   2,357,307   318,184  
  $ 1,962,085 $ 4,005,404 $ 478,865  

43





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

9.     

Share capital (continued):

 

 

(c)     

Stock-based compensation (continued):

The fair value of the options granted during the years ended December 31, 2012, 2011 and 2010 was determined using the Black-Scholes pricing model using the following weighted average assumptions:

    2012     2011     2010  
 
Share price $ 6.66   $ 7.10   $ 3.09  
Exercise price   6.66     7.10     3.09  
Risk-free interest rate   1.36%   2.56%   2.62%
Expected volatility   58.67%   71.94%   68.63%
Expected option life in years   5     5     5  
Expected option life in years   -     -     -  
                   

The weighted average grant-date fair value of options granted during the year ended December 31, 2012 was $3.37 per option (2011 - $4.29 per option; 2010 - $1.81 per option).

Expected volatility was estimated considering a five-year historic average share price volatility.

Expected dividends were determined to be nil, since it is the present policy of the Corporation to retain all earnings to finance operations.

10.     

Commitments and contingencies:

 

(a)     

Operating leases:

Minimum lease payments under non-cancelable operating leases that were entered into by the Corporation are payable as follows:

 
       
Less than one year $ 366,432  
Between one and five years   197,524
More than five years   2,904  
       
  $ 566,860   

In September 2012 and November 2010, the Corporation entered into new operating lease agreements for its Canadian and US premises, both of which will expire on August 31, 2014 and October 31, 2013, respectively.

44





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

10.     

Commitments and contingencies (continued):

 

(a)     

Operating leases (continued):

The current leases for the Canadian and U.S. operations run for two years and three years respectively, with an option to renew the leases after these dates. Lease payments are increased with every renewal to reflect market rentals. During the year ended December 31, 2012, an amount of $370,440 was recognized as an expense in respect of operating leases (2011 - $364,471; 2010 - $300,960).

(b)     

Contingencies:

In November 2011, two former directors of the Corporation, who ceased to be directors in 2006, served the Corporation with a Motion to Institute Proceedings filed with the Quebec Superior Court seeking an order that they are entitled to exercise options to purchase a total of 125,000 shares of the Corporation at a price of US$4.33 or, in the alternative, damages for lost profit. The Corporation believes that the right to exercise these options ended in May 2007 and that the claims are without merit. The Corporation intends to defend the action vigorously. Accordingly, no provision related to this matter has been recorded in these consolidated financial statements.

11.     

Cost of sales:

In 2012, expenses related to inventories recognized as cost of sales amounted to $85,075 (2011 - $108,372; 2010 - $102,547).

12.     

Research tax credits and grants and income taxes:

 

(a)     

Research tax credits and grants:

The Corporation was entitled to a grant from the U.S. Government under the Qualifying Therapeutic Discovery Project for its ongoing Phase III clinical trial program for NX-1207 for the treatment of benign prostatic hyperplasia. In April 2011, the Corporation received its full entitlement under this program in the amount of $244,479.

45





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

12.     

Research tax credits and grants and income taxes (continued):

(a)    

Research tax credits and grants (continued):

Unused federal research tax credits may be used to reduce future income tax expense, which are not recognized and expire as follows:

       
2018 $ 5,228  
2019   8,504
2020   23,093
2021   23,483
2022   53,537
2023   69,362
2024   22,561
2025   29,084
2026   66,314
2027   73,235
2028   71,538
2029   96,957
2030   174,430
2031   244,789
2032   287,333  
       
  $ 1,249,448  

 

(b)     

Income taxes:

     

 

    2012     2011     2010  
Current income tax expense for the year $   $   $ 2,423,054  
 
Recognition of previously unrecognized tax loss           (2,423,054 )
 
Current income tax expense            
 
Deferred tax expense:                  

Origination and reversal of temporary differences

  (1,620,431 )   (1,591,363 )   (1,834,000 )

Change in unrecognized deductible temporary differences

  1,620,431     1,591,363     1,834,000  

Deferred tax expense

           
                   
Total income tax expense $   $   $  

46





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

12.     

Research tax credits and grants and income taxes (continued):

 

(b)     

Income taxes (continued):

Reconciliation of effective tax rate:

    2012     2011     2010  
Net loss for the year, before income taxes $ (7,627,589 ) $ (9,652,389 ) $ (6,536,313 )
Domestic tax rate applicable to the Corporation   26.9%     28.4%     29.9%  
Income taxes at domestic tax statutory rate   (2,051,821 )   (2,741,278 )   (1,954,358 )

Change in unrecognized deductible temporary differences

  1,620,431     1,591,363     1,834,000  

Non-deductible expenses and other

  431,390     1,149,915     120,358  
                   
Income taxes $   $   $  

The Corporation’s applicable tax rate is the Canadian combined rates applicable in the jurisdictions in which the Corporation operates. The decrease is due to the reduction of the Federal income tax rate in 2012 from 16.5% to 15.0% and in 2011 from 18% to 16.5%.

As at December 31, 2012 and 2011, deferred tax assets not recognized were as follows:

    2012   2011   2010  
 
Deferred revenue $ 2,083,064 $ 2,787,199 $ 3,530,597
Tax loss carry forward   12,493,652   11,196,417   9,523,940
Property and equipment and patents   1,950,980   1,923,879   1,894,480
Research and development expenditures   2,031,077   1,799,941   1,581,539
Share issue costs   100,081   103,847   123,525  
                 
Income taxes $ 18,658,854 $ 17,811,283 $ 16,654,081   

Deferred tax assets have not been recognized in respect to these items because it is not probable that future taxable profit will be available against which the Corporation can utilize the benefits therefrom. The generation of future taxable profit is dependent on the successful commercialization of the Corporation’s products and technologies.

47





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

12.     

Research tax credits and grants and income taxes (continued):

 

(b)     

Income taxes (continued):

At December 31, 2012, the amounts and expiry dates of tax attributes for which no deferred tax assets were recognized are as follows:

    Federal   Provincial  
 
Research and development expenditures, without time limitation $ 5,370,332 $ 10,298,546
 
Losses carried forward:        

2014

  581,932   504,560

2015

  3,544,044   3,544,196

2026

  3,807,913   3,745,175

2027

  3,608,571   3,529,083

2028

  2,750,121   2,750,121

2029

  3,607,077   3,607,077

2031

  7,385,581   7,368,724

2032

  7,336,536   7,319,234  
    32,621,775   32,368,170
 
Other deductible temporary differences:        

Share issue costs

  372,050   372,050

Excess of tax value of intellectual property and patent fees over carrying value

  7,009,846   7,009,846

Excess of tax value of property and equipment over carrying value

  265,750   265,750

Deferred revenue

  7,743,733   7,743,733
 
US losses carried forward:        

2018

      2,781,408

2019

      1,077,985

2020

      813,001

2021

      664,129

2022

      522,140

2023

      564,484

2024

      353,204

2025

      264,237

2026

      355,198

2027

      372,942

2028

      351,224

2029

      86,251

2030

      541,457

2031

      479,755

2032

      144,018  
      $ 9,371,433  
           

48





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

13.     

Earnings per share:

Weighted average number of common shares outstanding:

    2012   2011   2010  
               
Issued common shares at January 1 32,993,302 32,573,856 31,283,778
Effect of stock options exercised 3,704 20,167
Effect of shares issued   179,179   117,408   656,806  
               

Weighted average number of common shares outstanding at December 31

  33,176,185   32,711,431   31,940,584  

Diluted loss per share was the same amount as basic loss per share, as the effect of options would have been anti-dilutive, because the Corporation incurred losses in each of the years presented. All outstanding options could potentially be dilutive in the future.

14.     

Capital disclosures:

The Corporation's objective in managing capital is to ensure a sufficient liquidity position to finance its research and development activities, general and administrative expenses, working capital and overall capital expenditures, including those associated with patents. The Corporation makes every attempt to manage its liquidity to minimize shareholder dilution when possible.

The Corporation defines capital as total equity. To fund its activities, the Corporation has followed an approach that relies almost exclusively on the issuance of common shares and, during 2010, entered into a collaboration agreement. Since inception, the Corporation has financed its liquidity needs primarily through private placements and, since 2003, through a financing agreement with an investment company that has been replaced annually by a new agreement with the same purchaser (see note 9 (a) - Common Stock Private Purchase Agreement). The Corporation intends to access financing under this agreement when appropriate to fund its research and development activities. The financial crisis in the United States and the global economic environment has had a negative impact on the availability of liquidity in the market. Since 2003 through to December 2012, the Purchaser has always complied with the drawdowns made pursuant to the agreement. The Corporation believes that cash balances, funds from operations, as well as funds from the Common Stock Private Purchase Agreement will be sufficient to meet the Corporation’s cash requirements for the next twelve months.

The Corporation must comply with general covenants in order to draw on its facility including maintaining its stock exchange listing and registration requirements and having no material adverse effects, as defined in the agreement, with respect to the business and operations of the Corporation.

49





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

14.     

Capital disclosures (continued):

The capital management objectives remain the same as for the previous fiscal year. When possible, the Corporation tries to optimize its liquidity needs by non-dilutive sources, including sales, collaboration agreements, research tax credits and interest income. The Corporation's general policy on dividends is to retain cash to keep funds available to finance its research and development and operating expenses. The Corporation has no debt.

The Corporation is not subject to any capital requirements imposed by external parties.

15.     

Financial risk management:

This note provides disclosures relating to the nature and extent of the Corporation’s exposure to risks arising from financial instruments, including foreign currency risk, credit risk, interest rate risk and liquidity risk, and to how the Corporation manages those risks.

(a)     

Foreign currency risk:

The Corporation uses the US dollar as its measurement currency because a substantial portion of revenues, expenses, assets and liabilities of its Canadian and US operations are denominated in US dollars. The Corporation’s equity financing facility is also in US dollars. Foreign currency risk is limited to the portion of the Corporation’s business transactions denominated in currencies other than the US dollar. The Canadian operation has transactions denominated in Canadian dollars, principally relating to salaries and rent. Additional variability arises from the translation of monetary assets and liabilities denominated in currencies other than the US dollar at each statement of financial position date. Fluctuations in the currency used for the payment of the Corporation’s expenses denominated in currencies other than the US dollar (primarily Canadian dollars) could cause unanticipated fluctuations in the Corporation’s operating results, but would not impair or enhance its ability to pay its Canadian dollar denominated obligations. The Corporation’s objective in managing its foreign currency risk is to minimize its net exposures to foreign currency cash flows by transacting with parties in US dollars to the maximum extent possible. The Corporation does not engage in the use of derivative financial instruments to manage its currency exposures.

Approximately 57% of expenses that occurred during the year ended December 31, 2012 (2011 – 66%; 2010 – 78%) were denominated in US dollars. Foreign exchange fluctuations had no meaningful impact on the Corporation’s results in 2012, 2011 or 2010.

50





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

15.     

Financial risk management (continued):

 

(a)     

Foreign currency risk (continued):

The following table provides significant items exposed to foreign exchange:

CA$   2012     2011  
 
Cash $ 167,006   $ 320,662  

Trade accounts receivable, other receivables and research tax credits receivable

  54,169     119,192  
Trade accounts payable and accrued liabilities   (389,256 )   (399,802 )
             
  $ (168,081 ) $ 40,052  

The following exchange rates were applied for the years ended December 31, 2012, 2011 and 2010:

  Average rate  
  (twelve months) Reporting date rate
 
US$ - CA$ - December 31, 2012 0.9996 0.9949
US$ - CA$ - December 31, 2011 0.9891 1.0170
US$ - CA$ - December 31, 2010 1.0299 0.9946

Based on the Corporation’s foreign currency exposures noted above, varying the above foreign exchange rates to reflect a 5% strengthening of the US dollar would have increased the net loss for the year ended December 31, 2012 by less than $5,000, assuming that all other variables remained constant.

An assumed 5% weakening of the US dollar would have had an equal but opposite effect on the amount shown above, on the basis that all other variables remained constant.

(b) Credit risk:

Credit risk results from the possibility that a loss may occur from the failure of another party to perform according to the terms of the contract. Financial instruments that potentially subject the Corporation to concentrations of credit risk consist primarily of cash and trade and other accounts receivable. Cash is maintained with high-credit quality financial institutions. For trade accounts receivable, the Corporation performs periodic credit evaluations and typically does not require collateral. Allowances are maintained for potential credit losses consistent with the credit risk, historical trends, general economic conditions and other information.

51





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

15.     

Financial risk management (continued):

 

(b)     

Credit risk (continued):

The Corporation has a limited number of customers. Included in the consolidated statement of financial position are trade accounts receivable of $30,732 (2011 - $31,546), all of which were aged under 45 days. Three customers (2011- four customers) accounted for 86.4% (2011 - 100%) of the trade receivables balance at December 31, 2012, all of whom have a good payment record with the Corporation. No bad debt expense was recorded for the year ended December 31, 2012, December 31, 2011 or December 31, 2010.

At December 31, 2012, the Corporation’s maximum credit exposure corresponded to the carrying amount of cash, trade accounts receivable and other receivables.

(c)     

Interest rate risk:

Interest rate risk is the risk that the fair value or future cash flows of a financial instrument will fluctuate because of changes in market interest rates. Cash bears interest at a variable rate. Trade accounts receivable, other receivables, trade accounts payable and accrued liabilities bear no interest. The Corporation has no other interest-bearing financial instruments.

Based on the value of variable interest-bearing cash during the year ended December 31, 2012, an assumed 0.5% increase or 0.5% decrease in interest rates during such period would have had no significant effect on the net loss.

(d)     

Liquidity risk:

Liquidity risk is the risk that the Corporation will not be able to meet its financial obligations as they fall due. The Corporation manages liquidity risk through the management of its capital structure, as outlined in note 14 - Capital disclosures. The Corporation does not have an operating credit facility and finances its activities through an equity financing agreement with an investment company, as described in note 9 (a) - Common Stock Private Purchase Agreement.

The following are the contractual maturities of financial liabilities:

    Carrying   Less than        
    amount   1 year     1 year to 5 years  
 
Trade accounts payable and accrued liabilities:              

December 31, 2012

$ 1,055,159 $ 1,055,159   $

December 31, 2011

  811,492   811,492    
                 

The redeemable preferred shares in the amount of $400,000 have no specific terms of repayment.

52





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

16.     

Financial instruments:

 

(a)     

Fair value disclosure:

The Corporation has determined that the carrying value of its short-term financial assets and liabilities approximates their fair value due to the immediate or short-term maturity of these financial instruments.

(b)     

Finance income and finance costs:

 
    2012     2011     2010  
 
Interest income $ 6,180   $ 12,817   $ 1,191  
 
Finance income   6,180     12,817     1,191  
 

Interest and bank charges

  (10,635 )   (11,700 )   (7,078 )

Net foreign exchange loss

  (28,483 )   (28,179 )   (25,294 )
Finance costs   (39,118 )   (39,879 )   (32,372 )
 
Net finance costs $ (32,938 ) $ (27,062 ) $ (31,181 )

 

17.     

Segment disclosures:

The Corporation operates in one reportable segment, which is the Corporation’s strategic business unit -the research and development of products for the aging population.

Information regarding the geographic reportable segment is as follows:

        United   Europe  
    Canada   States   and other  
 
Revenues:            

2012

$ 23,960 $ 353,397 $ 2,701,410

2011

  11,537   437,410   2,664,868

2010

  15,900   505,897   169,653
 
Property and equipment:            

December 31, 2012

  14,818   300  

December 31, 2011

  21,253   907    
               

Revenues are attributed to geographic locations based on location of customers.

53





NYMOX PHARMACEUTICAL CORPORATION
Notes to Consolidated Financial Statements, Continued
 
As of December 31, 2012 and 2011, and for each of the years in the three-year period ended
December 31, 2012
(In US dollars)
 

 

17.     

Segment disclosures (continued):

Major customers:

Customers that accounted for greater than 10% of revenues from sales in any of the last three years were as follows:

    2012   2011   2010  
 
Customer A $ 129,803 $ 191,190 $ 165,870
Customer B   -   -   143,950
Customer C   35,468   78,122   23,066
               

One customer accounted for 100% of licensing revenues during 2012, 2011, 2010 (refer to note 7).

18.     

Related parties:

Executive officers and directors participate in the Corporation’s stock option plan (see note 9 (b)). Executive officers are covered under the Corporation’s health plan.

Key management personnel compensation is comprised of:

    2012   2011   2010  
 
Salaries $ 630,346 $ 667,788 $ 565,320
Short-term employee benefits   9,719   9,259   10,619
Stock-based compensation   1,808,628   3,802,911   478,865
 
  $ 2,448,693 $ 4,479,958 $ 1,054,804  

 

19.     

Personnel expenses:

    2012   2011   2010  
 
Salaries $ 2,019,020 $ 1,801,253 $ 1,314,187
Employer contributions   175,360   164,988   116,601
Short-term employee benefits   50,305   44,244   43,785
Stock-based compensation   1,689,380   3,848,780   478,865  
 
  $ 3,934,065 $ 5,859,265 $ 1,953,438  

The table above includes the compensation figures from the table in note 18.

20.     

Subsequent events:

On February 4, 2013, the Corporation issued 153,610 common shares for gross proceeds of $1,000,000 under the Common Stock Private Purchase Agreement referred to in note 9 (a).

54