EXHIBIT 21.1

SUBSIDIARIES OF BIOSCRIP, INC.

Applied Health Care, LLC

BioScrip Infusion Management, LLC

BioScrip Infusion Services, Inc.

BioScrip Infusion Services, LLC

BioScrip Nursing Services, LLC

BioScrip PBM Services, LLC

BioScrip Pharmacy (NY), Inc.

BioScrip Pharmacy (Puerto Rico), Inc.

BioScrip Pharmacy Services, Inc.

BioScrip Pharmacy, Inc.

Bradhurst Specialty Pharmacy, Inc.

Cedar Creek Home Health Care Agency, Inc.

Chronimed LLC

CHS Holdings, Inc.

Critical Homecare Solutions, Inc.

Deaconess Enterprises, LLC

Deaconess HomeCare, LLC

East Goshen Pharmacy, Inc.

Elk Valley Health Services, Inc.

Elk Valley Home Health Care Agency, Inc.

Elk Valley Professional Affiliates, Inc.

Gericare, Inc.

Infusion Partners of Brunswick, LLC

Infusion Partners of Melbourne, LLC

Infusion Partners, LLC

Infusion Solutions, Inc.

Knoxville Home Therapies, LLC

National Health Infusion, Inc.

Natural Living, Inc.

New England Home Therapies, Inc.

Option Health, Ltd.

Professional Home Care Services, Inc.

Regional Ambulatory Diagnostics, Inc.

Scott-Wilson, Inc.

South Mississippi Home Health, Inc.

South Mississippi Home Health, Inc. – Region I

South Mississippi Home Health, Inc. – Region II

South Mississippi Home Health, Inc. – Region III

Specialty Pharma, Inc.

Wilcox Medical, Inc.