As filed with the Securities and Exchange Commission on December 19, 2012

File No. 333-02381/811-07589

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM N-1A

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933	x
Pre-Effective Amendment No.	¨
Post-Effective Amendment No. 115	x

and/or

REGISTRATION STATEMENT UNDER THE
INVESTMENT COMPANY ACT OF 1940	x
Amendment No. 116	x

THE HARTFORD MUTUAL FUNDS, INC.

(Exact Name of Registrant as Specified in Charter)

P. O. Box 2999, Hartford, Connecticut 06104-2999

(Address of Principal Executive Offices)

Registrant’s Telephone Number including Area Code: (860) 843-9934

Edward P. Macdonald, Esquire

The Hartford Financial Services Group, Inc.

Life Law – Mutual Funds Unit

200 Hopmeadow Street

Simsbury, Connecticut 06089

(Name and Address of Agent for Service)

Copy to:

John V. O’Hanlon, Esquire

Dechert LLP

200 Clarendon Street, 27^th Floor

Boston, Massachusetts 02116-5021

It is proposed that this filing will become effective (check appropriate box):

X	immediately upon filing pursuant to paragraph (b) of Rule 485
	on (Date) pursuant to paragraph (b) of Rule 485
	60 days after filing pursuant to paragraph (a)(1) of Rule 485
	on (Date) pursuant to paragraph (a)(1) of Rule 485
	75 days after filing pursuant to paragraph (a)(2) of Rule 485
	on (Date) pursuant to paragraph (a)(2) of Rule 485

If appropriate, check the following box:

  This post-effective amendment designates a new effective date for a previously filed

____ post-effective amendment.

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933 and the Investment Company Act of 1940, the Registrant certifies that it meets all of the requirements for effectiveness of this Registration Statement under rule 485(b) under the Securities Act of 1933 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Hartford, State of Connecticut, on the 19th day of December, 2012.

THE HARTFORD MUTUAL FUNDS, INC.
By:	/s/ James Davey
	James E. Davey Its: President

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed below by the following persons in the capacities and on the date indicated.

Signature	Title	Date
/s/ James Davey	President,	December 19, 2012
James E. Davey	Chief Executive  Officer
/s/ Mark A. Annoni	Controller & Treasurer	December 19, 2012
Mark A. Annoni	(Chief Accounting Officer &
	Chief Financial Officer)
*	Director	December 19, 2012
Lynn S. Birdsong
*	Chairman of the Board	December 19, 2012
Robert M. Gavin, Jr.	and Director
*	Director	December 19, 2012
Duane E. Hill
*	Director	December 19, 2012
Sandra S. Jaffee
*	Director	December 19, 2012
William P. Johnston
*	Director	December 19, 2012
David N. Levenson
*	Director	December 19, 2012
Phillip O. Peterson
*	Director	December 19, 2012
Lemma W. Senbet
*	Director	December 19, 2012
Lowndes A. Smith
/s/ Edward P. Macdonald		December 19, 2012
* By Edward P. Macdonald
Attorney-in-fact

* Pursuant to Power of Attorney dated February 1. 2012 (incorporated by reference to Post-Effective Amendment No. 102 to Registration Statement on Form N-1A (File No. 333-02381) filed on February 28, 2012).

EXHIBIT INDEX

Exhibit No.

EX-101.INS	XBRL Instance Document
EX-101.SCH	XBRL Taxonomy Extension Schema Document
EX-101.CAL	XBRL Taxonomy Extension Calculation Linkbase Document
EX-101.DEF	XBRL Taxonomy Extension Definition Linkbase Document
EX-101.LAB	XBRL Taxonomy Extension Labels Linkbase Document
EX-101.PRE	XBRL Taxonomy Extension Presentation Linkbase Document