SEC FORM 3

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

Simonian Nancy A

(Last)

(First)

(Middle)

MILLENNIUM PHARMACEUTICALS, INC.

40 LANDSDOWNE STREET

(Street)

CAMBRIDGE

02139

(City)

(State)

(Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
05/31/2007

3. Issuer Name and Ticker or Trading Symbol
MILLENNIUM PHARMACEUTICALS INC [ MLNM ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	Chief Medical Officer

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common stock	69,012	D
Common stock	4,424⁽¹⁾	I	by 401(k) plan account

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivative Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
Employee stock option (right to buy)	⁽²⁾	11/30/2011	Common stock	20,000	$34.09	D
Employee stock option (right to buy)	⁽²⁾	12/31/2011	Common stock	20,000	$24.51	D
Employee stock option (right to buy)	⁽²⁾	01/31/2012	Common stock	20,000	$19.01	D
Employee stock option (right to buy)	⁽³⁾	02/27/2012	Common stock	3,106	$19.49	D
Employee stock option (right to buy)	⁽³⁾	03/27/2012	Common stock	3,105	$22.04	D
Employee stock option (right to buy)	⁽⁴⁾	04/26/2012	Common stock	3,104	$18.42	D
Employee stock option (right to buy)	⁽⁵⁾	10/17/2012	Common stock	4,167	$7.99	D
Employee stock option (right to buy)	⁽⁵⁾	11/15/2012	Common stock	4,167	$8.27	D
Employee stock option (right to buy)	⁽⁶⁾	12/17/2012	Common stock	4,166	$9.35	D
Employee stock option (right to buy)	⁽⁷⁾	02/26/2013	Common stock	22,500	$6.88	D
Employee stock option (right to buy)	⁽⁸⁾	09/02/2013	Common stock	22,500	$14.68	D
Employee stock option (right to buy)	⁽⁹⁾	10/31/2013	Common stock	8,334	$15.92	D
Employee stock option (right to buy)	⁽¹⁰⁾	11/28/2013	Common stock	8,333	$15.83	D
Employee stock option (right to buy)	⁽¹¹⁾	12/31/2013	Common stock	8,333	$18.65	D
Employee stock option (right to buy)	⁽¹²⁾	02/25/2014	Common stock	31,250	$17.77	D
Employee stock option (right to buy)	⁽¹³⁾	09/01/2014	Common stock	31,250	$12.09	D
Employee stock option (right to buy)	⁽¹⁴⁾	09/23/2014	Common stock	100,000	$13.36	D
Employee stock option (right to buy)	⁽¹⁵⁾	01/31/2015	Common stock	4,167	$9.21	D
Employee stock option (right to buy)	⁽¹⁶⁾	02/28/2015	Common stock	4,167	$8.6	D
Employee stock option (right to buy)	⁽¹⁷⁾	03/03/2015	Common stock	160,000	$8.41	D
Employee stock option (right to buy)	⁽¹⁸⁾	03/31/2015	Common stock	4,166	$8.42	D

Explanation of Responses:

1. Reflects shares allocated to the reporting person's account under the company's 401(k) plan as of May 31, 2007.

2. Became exercisable for 1/4th of the total number of shares granted on 11/12/2002 and for 1/48th of the total number of shares granted monthly beginning 12/12/2002.

3. Became exercisable for 1/48th of the total number of shares granted monthly beginning 03/27/2002.

4. Became exercisable for 1/48th of the total number of shares granted on 04/26/2002 and for 1/48th of the total number of shares granted monthly beginning 04/27/2002.

5. Became exercisable for 1/53rd of the total number of shares granted monthly beginning 11/17/2002.

6. Became exercisable for 2/53rds of the total number of shares granted on 12/17/2002 and for 1/53rd of the total number of shares granted monthly beginning 01/17/2003

7. Became exercisable for 1/48th of the total number of shares granted monthly beginning 03/26/2003.

8. Became exercisable for 6/48ths of the total number of shares granted on 09/02/2003 and for 1/48th of the total number of shares granted monthly beginning 9/26/2003.

9. Becomes exercisable for 1/48th of the total number of shares granted monthly beginning 11/16/2003.

10. Becomes exercisable for 1/48th of the total number of shares granted on 11/28/2003 and for 1/48th of the total number of shares monthly beginning 12/16/2003.

11. Becomes exercisable for 2/48ths of the total number of shares granted on 12/31/2003 and for 1/48th of the total number of shares monthly beginning 01/16/2004.

12. Becomes exercisable for 1/48th of the total number of shares granted monthly beginning 03/25/2004.

13. Becomes exercisable for 6/48ths of the total number of shares granted on 09/01/2004 and for 1/48th of the total number of shares granted monthly beginning 09/25/2004.

14. Becomes exercisable for 1/48th of the total number of shares granted monthly beginning 10/23/2004.

15. Becomes exercisable for 1/48th of the total number of shares granted monthly beginning 02/17/2005.

16. Becomes exercisable for 1/48th of the total number of shares granted on 02/28/2005 and for 1/48th of the total number of shares monthly beginning 03/17/2005.

17. Became exercisable for 1/48th of the number of shares granted monthly beginning 04/03/2005 through 02/03/2007 and for 25/48ths of the shares on 03/03/2007.

18. Becomes exercisable for 2/48ths of the total number of shares granted on 03/31/2005 and for 1/48th of the total number of shares monthly beginning 04/17/2005.

Remarks:

	Joel S. Goldberg, Attorney-In-Fact	06/08/2007
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.