Exhibit 21.1

Subsidiaries of Progenity, Inc.

1. SPX3, Inc., a Delaware corporation

2. Molecular Diagnostic Health Sciences, LLC, a Delaware limited liability company

3. Progenity Holding Company, Inc., a Delaware corporation

4. Avero Laboratory Holdings LLC, a Delaware limited liability company

5. Progenity UK Limited, a private limited company incorporated in the United Kingdom

6. Progenity Pty Ltd, an Australian company